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- 克隆性:
单克隆
- 抗体英文名:
anti-VASH1(Vasohibin
- 抗体名:
兔抗血管抑制蛋白1抗体
VASH1 is a angiogenesis inhibitor. It inhibits migration, proliferation and network formation by endothelial cells as well as angiogenesis. This inhibitory effect is selective to endothelial cells as it does not affect the migration of smooth muscle cells or fibroblasts. It does not affect the proliferation of cancer cells in vitro, but inhibits tumor growth and tumor angiogenesis and acts in an autocrine manner. VASH1 also inhibits artery neointimal formation and macrophage infiltration and exhibits heparin-binding activity. There are two named isoforms.
mol wt:41kDa
Other Aliases:
Vasohibin 1; KIAA1036; VASHxy-0295Ms Mouse anti-rabbit IgG ascites小鼠抗兔IgG腹水
xy-0293Ms Mouse anti-rat IgG ascites小鼠抗大鼠IgG腹水
xy-0326Ms Mouse anti-Bovine IgG ascites小鼠抗牛IgG腹水
xy-0312Rs Rabbit anti-Avidin whole serum兔抗亲和素抗血清
xy-0311Rs Rabbit anti-Biotin whole serum兔抗生物素抗血清
xy-0327Rs Rabbit anti-Bovine IgM whole serum兔抗牛IgM抗血清
xy-0310Rs Rabbit anti-chicken IgG whole serum兔抗鸡IgG抗血清
xy-0314Rs Rabbit anti-chicken IgM whole serum兔抗鸡IgM抗血清
xy-0303Rs Rabbit anti-Dog IgG whole serum兔抗狗IgG抗血清
xy-0370Rs Rabbit anti-Goat IgM whole serum兔抗羊IgM抗血清
xy-0358Rs Rabbit anti-Guinea pig IgG whole serum兔抗豚鼠IgG抗血清
xy-0375Rs Rabbit anti-Guinea pig IgM whole serum兔抗豚鼠IgM抗血清
xy-0297Rs Rabbit anti-human IgG whole serum兔抗人IgG抗血清
xy-0345Rs Rabbit anti-human IgM whole serum兔抗人IgM抗血清
xy-0335Rs Rabbit anti-Monkey IgG whole serum兔抗猴IgG抗血清
xy-0336Rs Rabbit anti-Monkey IgM whole serum兔抗猴IgM抗血清
xy-0296Rs Rabbit anti-mouse IgG whole serum兔抗小鼠IgG抗血清
xy-0368Rs Rabbit anti-mouse IgM whole serum兔抗小鼠IgM抗血清
xy-0330Rs Rabbit anti-mouse Kappa Chain whole serum兔抗小鼠k-链抗血清
xy-0377Rs Rabbit anti-mouse IgG-Fc fragment whole serum兔抗小鼠IgG-Fc段抗血清
xy-0403Rs Rabbit anti-MG IgG whole serum兔抗长爪沙鼠IgG抗血清
xy-0297xys Donkey anti-human IgG whole serum驴抗人IgG抗血清
xy-0294xys Donkey anti-Goat IgG whole serum驴抗羊IgG抗血清
xy-0358xys Donkey anti-Gpig IgG whole serum驴抗豚鼠IgG抗血清
xy-0326Gs Goat anti-Bovine IgG whole serum羊抗牛IgG抗血清
xy-0326Rs Rabbit anti-Bovine IgG whole serum兔抗牛IgG抗血清
xy-0326G Goat Anti-Bovine IgG羊抗牛IgG
xy-0326M Mouse Anti-Bov IgG小鼠抗牛IgG
xy-0326R Rabbit Anti-Bov IgG兔抗牛IgG
xy-0310G Goat Anti-Chicken IgG羊抗鸡IgG
xy-0310R Rabbit Anti-chicken IgG兔抗鸡IgG
xy-0432M chicken IgY小鼠抗鸡IgY抗体
兔抗血管抑制蛋白1抗体
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文献和实验,包括α1抗胰蛋白酶、抗凝血酶、C1抑制剂和纤维蛋白溶解抑制剂等等。它们选择性作用于不同丝氨酸蛋白酶,其功能丧失将导致种种疾病。如:α1抗胰蛋白酶缺陷肺气肿或肝硬变;抗凝血酶缺陷血栓病;C1抑制剂缺陷血管水肿;神经抑丝酶包含体家族性脑病(FENIB)等。 分子内两个结构特征对抑丝酶抑制蛋白酶具有重要作用,一是显露的16氨基酸肽环,能被蛋白酶分解;二是由5 条肽链构成的β片层结构。抑丝酶发挥催化功能经过显著的构象变化。亚稳态活性状态的抑丝酶在同系蛋白酶的作用下形成酰基-酶,显露的肽环作为第6股肽
肿(emphysema)或 支气管哮喘 (bronchial asthma)统称为慢性阻塞性肺疾患(chronic obstructive pulmonary disease,COPD)。这类疾病以肺泡破坏、融合、呼吸面减少导致缺氧甚至肺心病为特征。大量调查表明,COPD的发生与吸烟有关。这是由于吸烟刺激巨噬细胞和中性粒细胞释放弹性蛋白酶,从而分解肺弹性蛋白之故,但远非吸烟者都患COPD。现在知道,COPD的产生也有一定的遗传基础。 正常人机体内存在一组能抑制蛋白酶活性的多肽
lapinization|兔化法[通过兔体使病毒等减毒] lapinized virus|兔化(病)毒 lariat|套索[真核mRNA剪接过程中形成的分枝状中间体] laser crosslinking|激光交联[通过紫外激光照射使蛋白质与核酸发生交联] lassa virus|拉沙病毒[属沙粒病毒科] late gene|晚期基因[可特指病毒] latency|潜伏状态 lateral
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