载脂蛋白D(apolipoprotein D,apoD)是一个29kDa的糖蛋白,它最初是在人血浆的高密度脂蛋白中被分离出来的。apoD在结构上与其他类型的载脂蛋白存在很大的差异,被归入脂肪促成素家族。apoD可以与胆固醇、、胆红素等多种疏水性小分子结合。
apoD在多种脊索动物的各类组织中广泛表达, 在脊椎动物中重要的生理功能。最近的研究表明,apoD可以作为多种癌症及神经系统疾病的早期诊断标记, apoD是一个多配体、多功能的蛋白质。
Apolipoprotein D (APO D), a glycoprotein involved in the human plasma lipid transport system. It is a progesterone binding glycoprotein of 24,000 dalton monomer molecular size, is a constituent of high density lipoprotein in plasma. The function of apolipoprotein D in the metabolism of plasma lipoproteins is unclear but the observation that this protein forms complexes with lecithin: cholesterol acyltransferase has led to the suggestion that apolipoprotein D may be involved in cholesterol esterification and transport of substrates and products of the reaction. Apolipoprotein D is expressed in a range of normal tissues including axillary apocrine glands, adrenal cortex and corpus luteum. Peripheral nerves, pituitary, testis, cerebellum and renal tubes are also positive. APO D was first isolated in large quantity as GCDFP 24, the major protein component of most human breast cyst fluids. In recent studies, Apo D immunoreactivity has been shown to be an early indicator of prostate cancer and advanced primary prostate tumors.xy-6762R LIPG内皮脂肪酶抗体
xy-4206R sLOX 1可溶性凝集素样氧化低密度脂蛋白受体1抗体
xy-7504R Laminin Beta 2层粘连蛋白β2抗体
xy-7516R LECT1白细胞衍生化学吸引素抗体
xy-8430R LMO2T淋巴细胞易位蛋白2抗体
xy-11463R Liprin alpha 1酪氨酸磷酸酶受体相互作用蛋白Liprin α1抗体
xy-4245R LONP1线粒体离子肽酶1抗体
xy-6230R LC3C微管相关蛋白轻链3C抗体
xy-5705R LZTS1假定肿瘤抑制亮氨酸拉链蛋白1抗体
xy-3827R LDHC(Cancer,testis antigen 32)乳酸脱氢酶LDH-C(肿瘤/睾丸抗原32)抗体
xy-6090R LUCA15肿瘤抑制基因LUCA15抗体
xy-9193R LST1淋巴细胞特异性转运蛋白1抗体
xy-4118R LEO1RNA聚合酶相关蛋白LEO1抗体
xy-5408R Phospho-LRP6(Thr1479)磷酸化低密度脂蛋白受体相关蛋白6抗体
xy-5406R phospho-LCK(Tyr394)磷酸化淋巴细胞特异性蛋白酪氨酸激酶抗体
xy-4117R LRP5低密度脂蛋白受体相关蛋白5抗体
xy-5407R phospho-LRP5(Thr1492)磷酸化低密度脂蛋白受体相关蛋白5抗体
xy-5409R phospho-LRP1(Ser4523)磷酸化低密度脂蛋白受体相关蛋白1抗体
xy-3948R LKB1苏氨酸蛋白激酶LKB1抗体
xy-9364R LMP7低分子量蛋白7抗体
xy-3861R LIM protein脂肪瘤相关蛋白抗体
xy-10374R Laminin subunit beta-4层粘连蛋白β4抗体
xy-10370R GnRH-associated peptide I黄体激素释放激素/促性腺激素释放激素抗体
xy-15492R LOX蛋白赖氨酸-6-氧化酶抗体
xy-15500R LTK白细胞酪氨酸激酶受体抗体
xy-12386R LMX1A同源盒转录因子LMX1A抗体
xy-12413R LTBP1转化生长因子β1结合蛋白1抗体
xy-12390R Manic Fringe狂躁基因同源蛋白MFNG抗体
xy-12391R Mib1E3泛素蛋白连接酶MIB1抗体
xy-12396R MAML1主导控制样蛋白1抗体
载脂蛋白D抗体