促代谢型谷氨酸受体5抗体

促代谢型谷氨酸受体5抗体产品类别

兔抗人、大、小鼠GRM5蛋白抗体

产品价格

0.2ml/890元

产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

促代谢型谷氨酸受体5抗体产品介绍

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
mol wt:132kDa
Other Aliases:
Glutamate receptor metabotropic 5; GPRC1E; GRM 5; GRM5; Metabotropic glutamate receptor 5; mGlu5; mGluR5; mGluR5a; mGluR5b.xy-0409R Leptin瘦素抗体
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促代谢型谷氨酸受体5抗体