DNA拓普西异构酶Ⅱ抗体

DNA拓普西异构酶Ⅱ抗体产品标准

浓缩液(1mg/1ml) 亲和纯化抗体

产品应用

WB=1:100-500 Elisa =1:200-1000 IP=1:20-100 IHC=1:100-500 （石蜡切片需做抗原修复）

DNA拓普西异构酶Ⅱ抗体产品介绍

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. The gene encoding this enzyme functions as the target for several anticancer agents and a variety of mutations in this gene have been associated with the development of drug resistance. Reduced activity of this enzyme may also play a role in ataxia-telangiectasia. [provided by RefSeq].
mol wt:168kDa
Other Aliases:
DNA topoisomeraseⅡα; DNA topoisomerase 2-alpha; DNA topoisomerase II, alpha isozyme; TOP2; TP2A; TOP2A; DNA topoisomerase II 170 kD; DNA topoisomerase II alpha isozyme; DNA Topoisomerase2; TOP 2A; TopII alpha; Topo II alpha; Topoisomerase DNA II alpha 170kDa; Topoisomerase II alpha 170 kDaxy-11700R HAP1舞蹈症相关蛋白1抗体
xy-11701R HIP1亨廷顿(舞蹈症)相互作用蛋白1抗体
xy-8602R HAO1葡萄糖氧化酶1抗体
xy-8603R HOXD9转录调节因子HOXD9抗体
xy-8414R HAGHL羟基酰谷胱甘肽水解酶样蛋白抗体
xy-8415R HEATR7B2热休克蛋白受体家族蛋白7B2抗体
xy-8416R HEBP2Heme结合蛋白2抗体
xy-8417R HEPACAM2肝细胞粘附分子2抗体
xy-8418R HEXDC氨基己糖苷酶D抗体
xy-8419R HHLA2HHLA2蛋白抗体
xy-7512R Hyp羟脯氨酸抗体
xy-7026R HSP10热休克蛋白10抗体
xy-6600R HMPH同源盒蛋白PRH抗体
xy-6603R HSD17B1羟类固醇脱氢酶17β抗体
xy-4281R HAUSP疱疹病毒相关泛素特异性蛋白酶7抗体
xy-5713R HOXA5同源异型盒基因HOXA5蛋白抗体
xy-3825R HP1 alpha异染色质蛋白1-α(HP1α)抗体
xy-3826R Histone H4组蛋白H4抗体
xy-3746R Acetyl-Histone H4(K12)乙酰化组蛋白H4抗体
xy-3768R Histone H3 (tri methyl K36) 三甲基化组蛋白H3抗体
xy-3769R Histone H3 (Di Methyl K36)二甲基化组蛋白H3抗体
xy-3770R Histone H3 (Di Methyl K4)二甲基化组蛋白H3K4抗体
xy-3772R Histone H3 (Di Methyl K9)二甲基化组蛋白H3K9抗体
xy-3773R Histone H3 (Tri Methyl K27)三甲基化组蛋白H3抗体
xy-3774R Acetyl-Histone H3(K23)乙酰化组蛋白H3抗体
xy-3775R Acetyl-Histone H3(K18)乙酰化组蛋白H3抗体
DNA拓普西异构酶Ⅱ抗体