参考文献
In Neurobiology, Cal-520® AM has been used to study:
» Neuron single action potentials in neocortical neurons both in vitro and in vivo, and associated voltage-dependent calcium channels[1]
» Superior colliculus in mice in conjunction with two-photon calcium imaging to visualize retinal ganglion cells in the superficial lamina[2]
» Aldolase C compartments in mice, looking at complex spike synchrony and its relation to sensory processing in awake animals[3]
» Neural circuits in brain slice and whole brain preparation, specifically looking at individual action potentials in vivo[4]
» Ca2+ dependent cell signaling pathways using cultured human neuroblastoma SH-SY5Y cells and high-speed video-microscopy[5]
In Cell Signaling, Cal-520® AM has been used to study:
» Intracellular calcium in sperm using the microplate reader platform as a means to quantitating parameters such as motility[6]
» Calcium signaling pathways in meniscus fibrochondrocytes by way of visualizing calcium localization and concentration[7]
» Ca2+ mediated cellular signaling in relation to inositol triphosphate and its flux through gap junctions[8]
» Retinal wave-mediated formation of calcium transients in Müller glial cells with focus on expression of GCaMP3[9]
» Ca2+ signaling pathways in zebrafish sperm, specifically looking at calcium flux resulting from cGMP-induced hyperpolarization[10]
In Cardiology, Cal-520® AM has been used to study:
» Sarcoplasmic reticulum insofar as its role in cardiac excitation-contraction coupling and calcium spark events[11]
» Optical mapping of calcium in cardiac tissue slices to develop a framework for future investigations into calcium transients[12]
» Sodium-calcium exchanger functionality and mechanism with regards to burst pacemaker activity in knockout mice[13]
» Pacemaker modulation in embryonic heart as a function of inositol-1,4,5-triphosphate receptors[14]
» Calcium current and the role of potassium channel-interacting protein 2 (KChIP2) in mice with regards to heart failure[15]