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- 2025年07月14日
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文献和实验Human Type 2 Neuropeptide Y Receptor Gene: Isolation and Characterization
Our interest in G-protein signaling events involved in the specialized functions of the retinal pigment epithelium led us to investigate the pattern of G-protein-coupled receptor expression in this cell type. We used reverse
The BB Rat as a Model of Human Type 1 Diabetes
The BB rat is an important rodent model of human type 1 diabetes (T1D) and has been used to study mechanisms of diabetes pathogenesis as well as to investigate potential intervention therapies for clinical trials. The Diabetes-Prone BB (BBDP
Cardiac-Specific Overexpression of Angiotensin II Type 1 Receptor in Transgenic Rats
This chapter describes the methods required for overexpression of the angiotensin II type I receptor (AT1 ) in cardiomyocytes of transgenic rats. This includes cloning of the transgenic construct consisting of the α-myosin heavy chain (MHC
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