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- 技术资料
- 抗体英文名：
Anti-Human CD22 FITC
- 规格：
25tests
of the siglec subgroup of the Ig superfamily. CD22 is a type I transmembrane glycoprotein
composed of two polypeptide chains, CD22α and CD22β, of 130 and 140 kDa respectively,
produced by alternative splicing of the CD22 gene. CD22 is expressed at high levels on
mature B cells and B cell lymphomas. The extracellular portion of CD22 contains seven
Ig-like domains, some of which are capable of binding ligands with sialic acid moieties
expressed on epithelial, endothelial, B and T cells. The intracellular portion of CD22
contains 6 tyrosine residues contained within immunotyrosine-based inhibitory motifs (ITIM) and
immunotyrosine-based activation-like motifs, which are phosphorylated upon B-cell receptor
engagement, which enables CD22 to participate in the positive and negative regulation of
B-cell receptor signaling.
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文献和实验Anti-CD22 Onconase: Preparation and Characterization
Antibodies can be conjugated to effector molecules to derive targeted therapeutics with properties such as cell-specific cytotoxicity. The murine anti-CD22 antibody RFB4 linked to a member of the ribonuclease A superfamily, Onconase (Onc
Anti-GFP/BrdU In Situ Immunostaining
Materials 24 well dishes Millicell 0.4 µm inserts (Millipore PICM01250) - coated with fibronectin Culture medium PBS Fixative: 4% paraformaldehyde in PBS (pH 7.6) Rabbit anti-GFP (Molecular Probes, A-11122) FITC-goat anti-rabbit
FITC荧光二抗？――EarthOx新型DyLight 488绿色荧光
FITC荧光二抗？――EarthOx新型DyLight 488绿色荧光 FITC（Fluorescein Isothiocyanate，异硫*酸荧光素）是一种绿色荧光团，在免疫学实验里，经常被用于荧光团标记到相应的检测分子，如抗体上。FITC的纯品为黄色或橙黄色结晶粉末，易溶于水和酒精溶剂。FITC分子量为389.4，最大吸收光波长为 490～495nm，最大发射光波长为520～530nm，呈现明亮的黄绿色荧光。FITC在冷暗干燥处可保存多年，是目前应用最广泛的荧
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