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- Alzheimer's Disease Copy Number PCR Array
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- 2026年02月13日
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- 详细信息
- 文献和实验
- 技术资料
- 服务名称：
Alzheimer's Disease Copy Number PCR Array
- 提供商：
SAB
Duplications: APP, CHRNA7, CR1, CYFIP1, NIPA1, NIPA2, OR4K2, TUBGCP5.
Behavior, Cognition, Learning & Memory: APP, ATXN1, CHRNA7, NRXN1.
Membrane Potential / Nerve Impulse: APP, ATXN1, CHRNA7, ERBB4, KLK6, NRXN1.
Amyloid Plaque Formation & Clearance: APP, CR1, CSMD1, FPR2, HLA-DPB1, KLK6.
Neurogenesis: APP, CYFIP1, NRXN1, RELN.
Central Nervous System Development: ERBB4, KLK6, NIPA1, NIPA2, RELN.
Axon Growth & Guidance: CYFIP1, RELN.
Neurotransmitter Receptor: CHRNA7.
Ion Transport: CHRNA7, NIPA1, NIPA2, SLC30A3, SLC35F2.
Immune Response: CR1, CSMD1, FPR2, HLA-DPB1.
Oxidative Stress Response: GSTT1.
Transcriptional Regulation: APP, ATXN1, ERBB4, MEOX2
G-Protein Coupled Receptors: FPR2, OR4K2.
Proteases: IMMP2L, KLK6, RELN.
Intracellular Transport: DOPEY2, IMMP2L.
Cell Adhesion & Cytoskeleton: CYFIP1, NRXN1, TUBGCP5
RNA Binding Proteins: ATXN1, HNRNPCL1.
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文献和实验from Illumina SNP array data using PennCNV and performing association analysis using R and PLINK. Curr. Protoc. Hum. Genet . 79:1.27.1?1.27.15. © 2013 by John Wiley & Sons, Inc. Keywords: copy number variations (CNV); CNV calling; genome
Targeted Screening and Validation of Copy Number Variations
. Methods covered include fluorescence in situ hybridization (FISH), quantitative real-time PCR (qPCR), paralogue ratio test (PRT), molecular copy-number counting (MCC), and multiplex PCR-based approaches, such as multiplex amplifiable probe hybridization
Detection of Copy Number Variation Using SNP Genotyping
have been identified as an important source of normal genomic variation as well as disease-causing variation. The ability to perform genome-wide discovery of large copy number variants (CNVs) has been facilitated by advances in two technologies – array comparative
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