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Mlkl antibody抗体,orb32399,biorb

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  • ¥3640
  • biorbyt已认证
  • orb32399
  • 英国
  • 2025年12月09日
  • ICC, IF, IHC-P, WB
  • Rabbit
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      Mlkl antibody抗体

    • 抗体英文名

      Mlkl antibody

    • 靶点

      Mlkl

    • 浓度

      - 100 μg (in 200 μl): 0.5 mg/ml- 200 μg (in 400 μl): 0.5 mg/ml

    • 应用范围

      ICC, IF, IHC-P, WB

    • 宿主

      Rabbit

    • 保质期

      6-12个月

    • 抗原来源

      详询

    • 目录编号

      orb32399

    • 级别

      科研级

    • 库存

      88

    • 供应商

      biorbyt

    • 标记物

      Unconjugated

    • 克隆性

      Polyclonal

    • 形态

      10 mM PBS, 0.02% sodium azide

    • 亚型

      IgG

    • 免疫原

      KLH conjugated synthetic peptide derived from human Mlkl. Please contact us for the exact immunogen sequence. The peptide is available as orb374793.

    • 规格

      100 ug

    产品描述:Mlkl antibody

    别名:anti-Mixed lineage kinase domain-like protein antibody, anti-Mlkl antibody

    免疫原:KLH conjugated synthetic peptide derived from human Mlkl. Please contact us for the exact 免疫原 sequence. The peptide is available as orb374793.

    分子量:54 kDa

    应用稀释比例:WB: 1:200-2000, IHC-P: 1:100-500, IF/ICC: 1:100-500

    纯度:Polyclonal antibodies are purified by peptide affinity chromatography

    保存说明:Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

    Pubmed:39052071, 38611943, 37329888, 34430820, 27756058, 30136227, 33247805, 29560122, 31754092, 31677207, 30742091, 32545631

    NCBI:001135969, 001142497

    Entrez:197259

    UniProt ID:Q9D2Y4, Q8NB16, D3ZKP6

    Note:For research use only.

    产品细节图片1
    IHC-P staining of human breast tumour tissue using Mlkl antibody (2.5 ug/ml)

    产品细节图片2
    Immunohistochemical staining of rat skin tissue using Mlkl antibody (2.5 ug/ml)

    产品细节图片3
    IHC-P image of human thyroid tumour tissue using Mlkl antibody (2.5 ug/ml)

    产品细节图片4
    Immunohistochemical staining of paraffin embedded rat thymus tissue using anti-Mlkl (2.5 ug/ml)

    产品细节图片5
    IHC-P staining of mouse lymph node tissue using anti-Mlkl (2.5 ug/ml)

    产品细节图片6
    WB analysis of rat heart (lane 1), mouse stomach (lane 2), rat liver (lane 3), rat spleen (lane 4), rat lung (lane 5), human breast cancer (lane 6) using Mlkl antibody (1 ug/ml)

    产品细节图片7
    Immunohistochemical staining of paraffin embedded rat stomach tissue using Mlkl antibody (2.5 ug/ml)

    产品细节图片8
    IF analysis of guinea pig heart tissue using anti-Mlkl (2.5 ug/ml)

    产品细节图片9
    Immunohistochemical staining of paraffin embedded guinea pig lung tissue using Mlkl antibody (2.5 ug/ml)

    产品细节图片10
    Western blot analysis of human breast tumour (lane 1), human thyroid tumour (lane 2), human lung cancer (lane 3), Hela cells (lane 4) using Mlkl antibody (1 ug/ml)

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    图标文献和实验
    该产品被引用文献
    Giusy Rita Caponio 1, Alessandro Annunziato 2, Mirco Vacca 2, Graziana Difonzo 2, Giuseppe Celano 2, Fabio Minervini 2, Marianna Ranieri 1, Giovanna Valenti 1, Grazia Tamma 1, Maria De Angelis Nutritional, antioxidant and biological activity characterization of orange peel flour to produce nutraceutical gluten-free muffins Food Funct, (2024), Xing Fan 1, Fang Lin 1, Yu Chen 2, Yuling Dou 1, Ting Li 1 3, Xinxin Jin 4, Jintao Song 2, Fang Wang Luteolin-7- O-β-d-glucuronide Ameliorates Cerebral Ischemic Injury: Involvement of RIP3/MLKL Signaling Pathway Molecules, (2024), Sublethal necroptosis signaling promotes inflammation and liver cancer Immunity, S1074-7613(23)00234-0 (2023), Zhang, Liansheng et al. BAD-mediated neuronal apoptosis and neuroinflammation contribute to Alzheimer's disease pathology iScience, 24, 102942 (2021), Günther, Claudia et al. The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis J Clin Invest, 126, 4346-4360 (2016), Saleh, Danish et al. Chemical Library Screens to Identify Pharmacological Modulators of Necroptosis Methods Mol. Biol., 1857, 19-33 (2018), Zhou, Huiling et al. RIP1/RIP3/MLKL-mediated necroptosis contributes to vinblastine-induced myocardial damage Mol Cell Biochem, 476, 1233-1243 (2021), Fuchslocher Chico, Johaiber et al. The enhanced susceptibility of ADAM-17 hypomorphic mice to DSS-induced colitis is not ameliorated by loss of RIPK3, revealing an unexpected function of ADAM-17 in necroptosis Oncotarget, 9, 12941-12958 (2018), Bittel, Miriam et al. Modulation of the extrinsic cell death signaling pathway by viral Flip induces acute-death mediated liver failure Cell Death Dis, 10, 878 (2019), Choi, Solji et al. 1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol ameliorates chemoradiation-induced oral mucositis Oral Dis, 26, 111-121 (2020), Frank, Tanja et al. Cell cycle arrest in mitosis promotes interferon-induced necroptosis Cell Death Differ, 26, 2046-2060 (2019), Stolberg-Stolberg, Josef et al. Cartilage Trauma Induces Necroptotic Chondrocyte Death and Expulsion of Cellular Contents Int J Mol Sci, 21, 4204 (2020)
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    ¥3640