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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
4°C, stored under nitrogen
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
1303607-07-9
- 规格:
10 mM * 1 mL/1 mg/5 mg/10 mg
| 规格: | 10 mM * 1 mL | 产品价格: | ¥1980.0 |
|---|---|---|---|
| 规格: | 1 mg | 产品价格: | ¥727.0 |
| 规格: | 5 mg | 产品价格: | ¥1600.0 |
| 规格: | 10 mg | 产品价格: | ¥2650.0 |
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MI-773
CAS No. : 1303607-07-9
MCE 国际站:MI-773
产品活性:MI-773 是一种有效的 MDM2-p53 蛋白质相互作用 (PPI) 抑制剂,对 MDM2 具体高结合亲和力 (Kd=8.2 nM)。MI-773 具有抗肿瘤活性。
研究领域:Apoptosis | Metabolic Enzyme/Protease
作用靶点:MDM-2/p53 | E1/E2/E3 Enzyme
In Vitro: SAR405838 (MI-77301), an analog of MI-773, displays 10 times higher binding affinity against MDM2 than MI-773 (Kd=62 vs 8.2 nM). The antitumor activity of MI-77301 is more pronounced in a set of wild type p53 xenograft models than MI-773, including SJSA-1 osteosarcoma, human prostate, melanoma, colorectal tumor, LNCAP human prostate tumor and human acute lymphoblastic leukemia.
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文献和实验、乙两液各按不同比例混合,即可得所需pH的缓冲液,见下表:pH 甲液ml 乙液mI5.29 2.5 97.55.59 5.0 95.05.91 10.0 90.06.24 20.0 80.06.47 30.0 70.06.64 40.0 60.06.81 50.0 50.06.98 60.0 40.07.17 70.0 30.07.38 80.0 20.07.73 90.0 10.08.04 95.0 5.0你要配制pH=6.8的PBS,可用甲、乙液各50ml混合即可。
网织红细胞的检测参数是临床医学检验技士考试需要了解的知识点,医学教育|网搜集整理了相关内容,希望对广大复习备考的考生有所帮助。 网织红细胞的检测参数: 1.RET%:网织红细胞百分比,来源于(网织红细胞数值÷所有红细胞数值)×100%,正常参考值为0.5%~2.5% 2.RET#:网织红细胞绝对值,来源于(网织红细胞百分比×红细胞数量),正常参考值为(0.02~0.1)×1012/L 3.IRF(MI):网织红细胞成熟度,来源于(不成熟的网织红细胞÷
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