ALZET Implantable Pumps 皮下植入胶囊

ALZET 缓释给药胶囊部分文献：

Basic fibroblast growth factor (FGF) promotes cartilage repair in vivo

... Alzet osmotic pumps delivering the mitogen to the site of injury promotes the healing of
intra-chondrial lesions by stimulating chondrocyte proliferation and the formation of extracellular matrix. ... Amer. J. Pathol., 81 (1975), pp. 337–346. Copyright © 1988 Published by Elsevier Inc. ...
 

An essential role for interferon gamma in resistance to Mycobact*erium tuberculosis infection.

... studies of murine IFN--y performed by Sharon Chen (Genentech, Inc., South San ... For continuous infusion, mice were subcutaneously implanted with osmotic pumps (Alza Corp., Palo Alto, CA...(B) gko mice were implanted subcutaneously with Alzet osmotic pumps loaded with IFN ...
 

 The in‐vivo evaluation of an osmotic device (Osmet) using gamma scintigraphy 

... 1 Alzet and Osmet are trademarks. ... DISCUSSION In the operation of the Osmet device, water is osmotically imbibed across the semipermeable mem- brane, swelling the osmotic
compartment and squeezing the drug reservoir uniformly along the axis. ...
 

… induced cell proliferation in rodent liver and kidney: a comparison of 5-bromo-2′-deoxyuridine and [3H] thymidine administered by injection or osmotic pump

... 2 h pulse 3 day pump 6 day pump 3 day pump; 3 weeks0 ... approximately 9 am, a second set of animals were implanted with pumps to deliver label for 3 days (Alzet models 1003D ... Product specifications state that osmotic pumps begin continuous delivery — 4 h after implantation. ...
 

Oral controlled‐release delivery of ivermectin in cattle via an osmotic pump

... Drug Delivery Device-Ivermectin was administered as a micel- lar solution contained within an ALZET 2ML4 mini-osmotic pump (ALZA Corp., Palo Alto ... The osmotic pumps were filled with the appropriate concen- tration of ivermectin solution to ensure that the defined dose ...
 

Osmotic drug delivery: a review of the patent literature

G Santus, RW Baker - Journal of Controlled Release, 1995 - Elsevier
... Water is drawn by osmosis into the salt chamber through semipermeable membrane. ... Coating containing solid osmotic compound ... Small pumps of this form are sold under the trade name Alzet® and are frequently used as implantable controlled-release delivery systems in ...
 

The impact of co-solvents and the composition of experimental formulations on the pump rate of the ALZET® osmotic pump

... the aqueous sodium chloride solution was needed for the initiation of the pumping and was ...facilitating the screen of lipophilic, poorly water-soluble compounds in osmotic pump studies ... ALZET,1992; ALZET Osmotic Pumps, Technical Information Manual, ALZA Corporation, 1992 ...
 

Identification of sulfated oligosaccharide-based inhibitors of tumor growth and metastasis using novel in vitro assays for angiogenesis and heparanase activity

... 88 was continually administered to the animals by ip-inserted 14-day Alzet mini-osmotic ... Detected by phycoerythrin-coupled rabbit F(ab′) 2 antimouse immunoglobulin (DAKO Corp., Carpinteria, CA ... at a dose of 20 mg/kg/day via ip 7-day mini-osmotic pumps (Alza Corporation). ...
 

Correlation of iron and zinc levels with lesion depth in newly formed atherosclerotic lesions

... Six weeks into the high cholesterol diet, two groups were treated with the iron chelating agent desferrioxamine, for 2 weeks and 4 weeks, respectively, by surgically implanting with Alzet osmotic pumps (Alza Corporation, Palo Alto, CA, USA) containing desferal (0.5 g/ml). ...