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文献和实验Purification and Molecular Analysis of Hemoglobin by High-Performance Liquid Chromatograpy
and two identical β-chains. Besides HbA, human erythrocytes contain small amounts of other forms of Hb as fetal hemoglobin (HbF, α2 γ2 ) and HbA2 (α2 δ2 ), and products of posttranslational modifications as HbA1c . HbS, the sickle cell Hb, is a genetic variant
. Performance of HbA1c for detecting newly diagnosed diabetes and pre-diabetes in Chinese communities living in Beijing. Diabet Med, 2009,26:1262-1268. [19] Zhou X, Pang Z, Gao W, et al. Performance of an A1C and fasting capillary blood glucose test
监测:包括每次持续至少2天的连续血糖监测4次,及每周3次的每日7次指尖血糖监测,连续血糖监测与指尖血糖监测数据具有良好相关性。留取基线和第三个月末糖化血红蛋白标本进行中心化测定。通过获得的近2700个血糖值计算,线性回归分析显示平均血糖与糖化血红蛋白密切相关: AGmg/dl(平均血糖)= 28.7 X A1C - 46.7, (R 2= 0.84, P 线性回归方程不受年龄、种族、性别、糖尿病类型及吸烟影响。 因此,本实验认为无论1型和2型糖尿病,HbA1c水平可以推测
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