产品封面图
文献支持

Recombinant Human Brain-Derive

d Neurotrophic Factor
收藏
  • ￥1080 - 79695
  • PROSPEC
  • 以色列
  • cyt-207
  • 2025年07月18日
    avatar
    上海经科化学科技有限公司
    16 年钻石会员

  • 企业认证

    点击 QQ 联系

    • 相关产品推荐更多 >

    万千商家帮你免费找货

    0 人在求购买到急需产品
    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件：

      for future use below -18°C

    • 保质期：

      See instructions

    • 英文名：

      BDNF

    • 库存：

      部分小规格有备货

    • 供应商：

      上海经科化学科技有限公司

    • 规格：

      2ug/10ug/1mg

    规格：2ug产品价格：￥1080.0
    规格：10ug产品价格：￥2415.0
    规格：1mg产品价格：￥79695.0

    产品细节图片1

    CATALOGUE NUMBER

    CYT-207

    SYNONYMS

    Brain-Derived Neurotrophic Factor, BDNF, MGC34632.

    INTRODUCTION

    BDNF promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. BDNF is a major regulator of synaptic transmission and plasticity at adult synapses in many regions of the cns. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (ltp), long-term depression (ltd), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

    DESCRIPTION

    Brain-derived Neurotrophic Factor Human Recombinant produced in E.Coli is a homodimer, non-glycosylated, polypeptide chain containing 2 x 119 amino acids (and an N-terminal Met) and having a total molecular mass of 27kDa.
    BDNF Human Recombinant is purified by proprietary chromatographic techniques.

    SOURCE

    Escherichia Coli.

    PHYSICAL APPEARANCE

    Sterile Filtered White lyophilized (freeze-dried) powder.

    FORMULATION

    The protein was lyophilized without any additives.

    SOLUBILITY

    It is recommended to reconstitute the lyophilized BDNF in sterile 18M-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

    STABILITY

    Lyophilized BDNF although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution BDNF should be stored at 4°C between 2-7 days and for future use below -18°C.
    For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
    Please prevent freeze-thaw cycles.

    PURITY

    BDNF is greater than 97.0% as determined by:
    (a) Analysis by RP-HPLC.
    (b) Analysis by SDS-PAGE.

    AMINO ACID SEQUENCE

    MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR.

    BIOLOGICAL ACTIVITY

    The ED50, as determined by the dose-dependent induction of C6 cells proliferation, is 1.3-2µg/ml.

    PROTEIN CONTENT

    BDNF quantitation was carried out by two independent methods:
    1. UV spectroscopy at 280 nm using the absorbency value of 1.6 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics).
    2. Analysis by RP-HPLC, using a standard solution of Brain-derived Neurotrophic Factor as a Reference Standard.

    风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标文献和实验
    该产品被引用文献

    Title:Generation of Neurons with Improved Cell Survival and Phenotype Maintenance Using a Degradation-Resistant Nurr1 Mutant
    Publication:Article first published online: 11 JUN 2009 DOI: 10.1002/stem.146 Copyright © 2009 AlphaMed Press.

    相关实验
    查看更多相关实验 >

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    BRAIN-DERIVED NEUROTROPHIC FACTOR HUMAN RECOMBINANT
    询价
    西宝生物科技(上海)股份有限公司
    2025年07月07日询价
    Brain derived neurotrophic factor (human), (recombinant)
    询价
    深圳欣博盛生物科技有限公司
    2025年05月20日询价
    Recombinant Human BDNF/Brain-derived neurotrophic factor
    ¥1680
    江西江蓝纯生物试剂有限公司
    2025年06月02日询价
    Recombinant Human Brain-Derived Neurotrophic Factor, HEK
    ￥1080
    上海经科化学科技有限公司
    2025年07月18日询价
    Recombinant Human Brain Derived Neurotrophic Factor (BDNF)
    询价
    默瑞（上海）生物科技有限公司
    2025年07月15日询价
    文献支持
    Recombinant Human Brain-Derived Neurotrophic Factor
    ￥1080 - 79695