- ￥3000 - 3999
- Abbiotec
- 美国
- 253531
- 2025年11月07日
- E, WB, ICC
- Rabbit
- H, M
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 免疫原：
KLH-conjugated synthetic peptide encompassing a sequence within human TSC2.
- 亚型：
Rabbit Ig
- 形态：
Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
- 保存条件：
Store at -20°C.
- 克隆性：
多克隆
- 标记物：
见下方详细说明
- 适应物种：
H, M
- 保质期：
1-2年
- 抗原来源：
KLH-conjugated synthetic peptide encompassing a sequence within human TSC2.
- 目录编号：
253531
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Rabbit
- 应用范围：
E, WB, ICC
- 浓度：
见详细说明信息
- 靶点：
TSC2
- 抗体英文名：
TSC2 Antibody
- 抗体名：
TSC2 Antibody
- 规格：
0.1 mg
TSC2 Antibody产品详细介绍：
| 产品名称： | TSC2 Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 253531 |
| 规格： | 0.1 mg |
| 产品描述： | Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. TOR activity is stimulated by Rheb, a member of the Ras superfamily of G-proteins, when the GTP/GDP ratio bound to Rheb is high. Immunoprecipitated TSC1/TSC2 has been shown to stimulate Rheb GTPase activity in vitro, suggesting that the TSC1/TSC2 complex decreases the ability of Rheb to stimulate TOR activity. This is supported by experiments showing that overexpression of TSC1 and TSC2 results in a significant decrease in the GTP/GDP ratio bound to Rheb and the inhibition of cell growth. At least three isoforms of TSC2 exist. |
| 克隆类型： | Rabbit Polyclonal Antibody |
| 亚型： | Rabbit Ig |
| 免疫原： | KLH-conjugated synthetic peptide encompassing a sequence within human TSC2. |
| 适用物种： | H, M |
| 应用范围： | E, WB, ICC |
| 应用说明： | E: 1:500-1:1,000; WB: 1:100-1:500; ICC: 1:100-1:500 |
| 别名： | TSC2 ; Tuberous sclerosis complex 2; Tuberin |
| 形态： | Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography. |
| 保存条件： | Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment. |
| 参考文献： |
ABBIOTEC产品提供质量保证，提供完善的售后和技术支持，ABBIOTEC产品正品包装：
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
TSC2 Antibody_TSC2抗体
￥3000 - 3999
