- ￥3000 - 3999
- Abbiotec
- 美国
- 252635
- 2025年07月12日
- WB, IHC
- Mouse
- H
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
Purified recombinant fragment of human ER-alpha (410-592aa) expressed in E. coli.
- 亚型：
Mouse IgG1
- 形态：
Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography.
- 保存条件：
Store at -20°C
- 克隆性：
单克隆
- 标记物：
见下方详细说明
- 适应物种：
H
- 保质期：
1-2年
- 抗原来源：
Purified recombinant fragment of human ER-alpha (410-592aa) expressed in E. coli.
- 目录编号：
252635
- 级别：
超纯
- 库存：
大量
- 供应商：
Abbiotec
- 宿主：
Mouse
- 应用范围：
WB, IHC
- 浓度：
见详细说明信息
- 靶点：
ER-alpha (2B7)
- 抗体英文名：
ER-alpha (2B7) Antibody
- 抗体名：
ER-alpha (2B7) Antibody
- 规格：
0.1 mg
ER-alpha (2B7) Antibody产品详细介绍：
| 产品名称： | ER-alpha (2B7) Antibody |
| 说明书： | 【点击查看详细说明及参考图片】 |
| 货号： | 252635 |
| 规格： | 0.1 mg |
| 产品描述： | Estrogen and progesterone receptors are members of a family transcription that are regulated by the binfing of their cognate ligands. The interaction of hormone bound estrogen receptors with estrogen responsive elements (EREs) alters transcription of ERE-containing genes. The carboxy terminal region of the estrogen receptor contains the ligand binding domain, the amino terminus serves as the transactivation domain and the DNA binding domain is centrally located. Two forms of estrogen receptor have been identified, ER alpha and ER beta. Both have been shown to be differentially activated by various ligands. The biological response to progesterone is mediated by two distinct forms of the human progesterone receptor (hPR-A and hPR-B) which arise from alternative splicing. In most cells, hPR-B functions as a transcriptional activator of progesterone-responsive gene, whereas hPR-A functions as a transcriptional inhibitor of all steroid hormone receptors. |
| 克隆类型： | Mouse Monoclonal Antibody |
| 亚型： | Mouse IgG1 |
| 免疫原： | Purified recombinant fragment of human ER-alpha (410-592aa) expressed in E. coli. |
| 适用物种： | H |
| 应用范围： | WB, IHC |
| 应用说明： | WB: 1:500-1:2000; IHC: 1:200-1:1000 |
| 别名： | Estrogen receptor; ER; Estradiol receptor; ER-alpha; Nuclear receptor subfamily 3 group A member 1; ESR1; ESR; NR3A1 |
| 形态： | Each vial contains 0.1 mg IgG in PBS pH7.4 with 0.03% sodium azide. Antibody was purified by Protein-G affinity chromatography. |
| 保存条件： | Store at 4°C for short term use only. Store at -20°C for storage over 1 month. Product is guaranteed 6 months from the date of shipment. |
| 参考文献： |
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文献和实验。 3 检测方法 3.1 酶免和放免法 酶免法采用双抗体夹心, 用人工合成的PCT 单克隆抗体检测。方法较特异, 无交叉反应。放免法利用由人工合成的57个氨基酸部分制成的R2B7特异性多克隆抗体, 既能检验游离型PCT, 又能检测结合型PCT, 比酶免法提高了灵敏度, 但耗时较长, 且标记的放射性元素存在污染, 因此限制了放免法的临床应用。 3.2 金标法 实验室多采用一种半定量检测PCT 的金标法。此法用一个结合有胶体金的抗降钙素的单克隆小鼠抗体和抗
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