GOLPH1 Antibody

GOLPH1 Antibody

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  • ¥3000 - 3999
  • Abbiotec已认证
  • 美国
  • 254156
  • 2025年07月14日
  • E, WB
  • Rabbit
  • H
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    • 详细信息
    • 技术资料
    • 免疫原

      KLH-conjugated synthetic peptide encompassing a sequence within human GOLPH1.

    • 亚型

      Rabbit Ig

    • 形态

      Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.

    • 保存条件

      Store at -20°C.

    • 克隆性

      多克隆

    • 标记物

      见下方详细说明

    • 适应物种

      H

    • 宿主

      Rabbit

    • 应用范围

      E, WB

    • 浓度

      见详细说明信息

    • 靶点

      GOLPH1

    • 抗体英文名

      GOLPH1 Antibody

    • 抗体名

      GOLPH1 Antibody

    • 规格

      0.1 mg

    GOLPH1 Antibody
    GOLPH1 Antibody产品详细介绍:
    产品名称: GOLPH1 Antibody
    说明书: 点击查看详细说明及参考图片
    货号: 254156
    规格: 0.1 mg
    产品描述: GOLPH1, also known as GCP60, was initially identified as a Golgi protein that can interact with the integral membrane protein giantin and is thought to be involved in the maintenance of the Golgi structure. GOLPH1 has also been shown to interact with other Golgi proteins such as Golgin-160, a Golgi protein that can be cleaved by caspases-2, -3, and -7, leading to the nuclear localization of Golgin-160. GOLPH1 interaction with the Golgin-160 fragments is stronger than that with the intact Golgin-160, with its interaction regulated by the oxidation state of Cys-463 within GOLPH1, suggesting that the nuclear localization of the caspase-cleaved Golgin-160 fragments is a highly coordinated event. GOLPH1 has also been found to interact with Numb, a cytosolic signaling protein that mediates asymetric cell division of neural progenitor cells to a daughter progenitor cell and a neuron, suggesting that Golgi fragmentation and reconstitution during the cell cycle differentially regulate Numb signaling through changes in GOLPH1 subcellular distribution and may couple cell fate with cell cycle progression.
    克隆类型: Rabbit Polyclonal Antibody
    亚型: Rabbit Ig
    免疫原: KLH-conjugated synthetic peptide encompassing a sequence within human GOLPH1.
    适用物种: H
    应用范围: E, WB
    应用说明: E: 1:500-1:1,000; WB: 1:100-1:500
    别名: GOLPH1; Golgi phosphoprotein 1; golgi complex-associated protein 1; GOCAP1; GCP60; acyl CoA binding domain containing 3; ACBD3
    形态: Each vial contains 0.1 ml IgG in PBS pH 7.4 with 0.02% sodium azide. Antibody was purified by immunogen affinity chromatography.
    保存条件: Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
    参考文献:

    ABBIOTEC产品提供质量保证,提供完善的售后和技术支持,ABBIOTEC产品正品包装:
    GOLPH1 Antibody GOLPH1 Antibody

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