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- 详细信息
- 文献和实验
- 技术资料
- 保质期：
1年
- 英文名：
MUTANT P53 REACTIVATOR, RETRA
- 供应商：
北京智杰方远科技
- CAS号：
******
- 保存条件：
详见说明
- 规格：
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文献和实验Generation and Characterization of p53 Mutant Mice
of the p53 knock-out mouse demonstrated the protein’s dispensability during embryogenesis, while highlighting its essential role in controlling tumor formation. A variety of p53 mutant models have emerged since the original p53 knock-out mouse
Lung-Specific Expression of Mutant p53 as Mouse Model for Lung Cancer
The p53 tumor suppressor gene is the most commonly mutated gene in cancer (1 ,2) and is mutated in 50% non-small cell lung cancer (NSCLC) and 70% of small cell lung cancer (SCLC) (3) . Mutations in p53 commonly reflect exposures
Detection of K-ras and p53 Mutations by Mutant-Enriched PCR-RFLP
, since they fulfill many criteria that link their de novo appearance to the process of field cancerization (4 ). Oncogene mutations of the ras - and p53 -type are found in chronic smokers and patients with preneoplastic and neoplastic lesions
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