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- 详细信息
- 文献和实验
- 技术资料
- 英文名:
SIRT1 Direct NAD+
- 库存:
1
- 供应商:
甄准生物
- 保存条件:
-80.0
- 规格:
1 ea
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文献和实验Methods to Investigate the Role of SIRT1 in Endothelial Senescence
Sirtuins are a family of proteins with NAD+ -dependent deacetylase or mono-ADP-ribosyltransferase activity. SIRT1, the mammalian ortholog most closely related to Sir2 (the first gene of this family discovered in yeast), exhibits anti
三句话读懂一篇 CNS:长期玩手机,伤脑又折寿;运动、做家务和社交活动可降低痴呆风险
联合在 Nature Immunology 发表研究论文 Deactylation by SIRT1 enables liquid–liquid phase separation of IRF3/IRF7 in innate antiviral immunity。 该研究将发现 SIRT1 介导的 DNA 结合域(DBD)去乙酰化是 IRF3/7 激活的关键步骤,其激活在衰老过程中受到抑制。通过使用 SIRT1 激动剂来改善 IRF3/IRF7 LLPS 的治疗方法,或可逆转老年人的先天
Introduction: Sirtuins in Aging and Diseases
) was proportional to the SIR2 gene dosage. Subsequent studies have shown that SIR2 homologs also slow aging in C. elegans , Drosophila , and mice. An important insight into the function of sirtuins came from the finding that yeast Sir2p and mammalian SIRT1 are NAD
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