D-erythro-N,N,N-Trimethylsphin

1) Cat. No.: TRC-T797150; 2) Chemical Name: D-erythro-N,N,N-Trimethylsphingosine Chloride; 3) CAS No.: 134962-48-4; 4) Mol. Formula: C21H44ClNO2; 5) Mol. Weight: 378.03; 6) Packing Size: 10mg / 100mg; 7) Appearence: White Solid; 8) Application Notes: Has an inhibitory effect via blocking of transmembrane signaling on the growth of various human tumor cell lines in vitro as well as in vivo in nu/nu mice. A potent and effective cardioprotective agent that inhibits leukocyte-endothelial cell interactions and preserves cardiac contractile function and coronary perfusion following myocardial ischemia and reperfusion.; 9) Synonym: [R-[R*,S*-(E)]]-1,3-Dihydroxy-N,N,N-trimethyl-4-octadecen-2-aminium Chloride;; 10) Solubility: Methanol, Water; 11) Storage condition: -20˚C Freezer; 12) References: Handa, K., et al.: Biochemistry, 30, 50, 11684 (1991), Endo, K., et al.: Cancer Research, 51, 1613 (1991), Park, Y.S., et al.: Cancer Research, 54, 2213 (1994), Kennedy, S.D., et al.: Am. J. Clin. Pathol., 107, 1, 99 (1997), Campbell, B., et al: Cardivasc. Res., 39, 2, 393 (1998),