(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin
-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine

(2Z)-4-Oxo-4-[3-(trifluorometh

yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin -7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine
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  • 询价
  • TRC已认证
  • 进口原装
  • TRC-O865000
  • 2025年07月13日
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    • 详细信息
    • 技术资料
    • 英文名

      (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin -7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine

    • 库存

      1

    • 供应商

      甄准生物

    • CAS号

      767340-03-4

    • 保存条件

      Refrigerator

    • 规格

      5mg / 50mg

    1) Cat. No.: TRC-O865000; 2) Chemical Name: (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin -7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine; 3) CAS No.: 767340-03-4; 4) Mol. Formula: C16H13F6N5O; 5) Mol. Weight: 405.3; 6) Packing Size: 5mg / 50mg; 7) Appearence: White Solid; 8) Application Notes: Sitagliptin intermediate. A dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for the treatment of diabetes and hypertension. ; 9) Synonym: (2Z)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one; 2,3-Desdihydrogen rac-Sitagliptin ; 10) Solubility: DMSO, Methanol; 11) Storage condition: Refrigerator; 12) References: Kim, D., et al.: J. Med. Chem., 48, 141 (2005), Ahren, B., et al.: Eur. J. Pharmacol., 521 164 (2005), Bergman, A., et al: Clin. Ther., 28, 55 (2006)

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    (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin -7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine
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