CI-988

1) Cat. No.: TRC-C432695; 2) Chemical Name: CI-988; 3) CAS No.: 130332-27-3; 4) Mol. Formula: C35H42N4O6; 5) Mol. Weight: 614.73; 6) Packing Size: 100mg / 250mg; 7) Appearence: ; 8) Application Notes: CI-988 is a potent and selective cholecystokinin 2 (CCK-2) receptor antagonist that displays ~ 1600-fold selectivity over CCK1 receptors and has negligible affinity at other binding sites. CI-988 exhibits anxiolytic activity following oral administration. CI-98 inhibited the proliferation of small cell lung cancer (SCLC) cells in mice.; 9) Synonym: 4-[[(1R)-2-[[(2R)-3-(1H-Indol-3-yl)-2-methyl-1-oxo-2-[[(tricyclo[3.3.1.13,7]dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]-4-oxobutanoic Acid; CI 988; [R-(R*,R*)]-4-[[2-[[3-(1H-Indol-3-yl)-2-methyl-1-oxo-2-[[(tricyclo[3.3.1.13,7]dec-2-yloxy)carbonyl]amino]propyl]amino]-1-phenylethyl]amino]-4-oxobutanoic Acid;; 10) Solubility: ; 11) Storage condition: ; 12) References: Drysdale, M. et al.: Bioorg. Med. Chem. Lett., 2, 45 (1992); Moody, T.W. et al.: J. Pharmacol. Exp. Ther., 299, 1154 (2001);