BML-286

1) Cat. No.: TRC-B595870; 2) Chemical Name: BML-286; 3) CAS No.: 294891-81-9; 4) Mol. Formula: C22H18N2O4; 5) Mol. Weight: 374.39; 6) Packing Size: 50mg / 500mg; 7) Appearence: ; 8) Application Notes: A small molecule inhibitor of the PDZ domain of Dishevelled (Dvl): an essential protein in the Wnt signaling pathways. This compound reduced the levels of apoptosis in the hyaloid vessels of the eye and also suppressed the growth of prostate cancer PC-3 cells. It is a useful tool for studies dissecting the Wnt signaling pathways.; 9) Synonym: 2-[[3-[(2-phenylacetyl)amino]benzoyl]amino]benzoic Acid; 2-[[3-[(phenylacetyl)amino]benzoyl]amino]benzoic Acid;; 10) Solubility: ; 11) Storage condition: ; 12) References: Grandy, D. et al.: J. Biol. Chem., 284, 24 (2009);