Anti-iNOS 抗体 [NOS-IN]产品图
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Anti-iNOS 抗体 [NOS-IN]

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  • ¥3869
  • Abcam
  • ab49999
  • 2026年08月31日
  • Mouse
  • Mouse
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名:

      Inosl, Nos2, Inducible NO synthase, Macrophage NOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2, Inducible NOS, iNOS, MAC-NOS

    • 宿主:

      Mouse

    • 适应物种:

      Mouse

    • 供应商:

      广州市左克生物

    • 规格:

      50µL

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    产品简介:

    品牌:abcam

    货号:ab49999

    产品名称:Anti-iNOS 抗体 [NOS-IN]

    产品规格:50µL

    应用:WB, ICC/IF

    种属反应性:Mouse

    宿主种属:Mouse

    产品概述HTML:

    Anti-iNOS antibody [NOS-IN] (ab49999) is a mouse monoclonal antibody detecting iNOS in Western Blot, ICC/IF. Suitable for Mouse.

    - Over 80 publications
    - Trusted since 2007

    查看别名

    Inosl, Nos2, Inducible NO synthase, Macrophage NOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2, Inducible NOS, iNOS, MAC-NOS

    隐藏别名:Inosl, Nos2, Inducible NO synthase, Macrophage NOS, NOS type II, Peptidyl-cysteine S-nitrosylase NOS2, Inducible NOS, iNOS, MAC-NOS

    关键信息HTML:

    关键信息

    宿主种属

    Mouse

    克隆

    Monoclonal

    克隆号

    NOS-IN

    亚型

    IgG1

    不含载体蛋白

    No

    反应种属

    Mouse

    应用

    WB, ICC/IF

    applications

    免疫原

    Synthetic Peptide within Mouse Nos2 aa 1100 to C-terminus conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.

    P29477

    特异性

    This antibody reacts specifically with inducible-type nitricoxide synthase (iNOS, also termed macNOS and mNOS). It does not react with NOS derived from brain.

    反应性数据HTML:

    反应性数据

    { "title": "Reactivity Data", "filters": { "stats": ["", "Species", "Dilution Info", "Notes"], "tabs": { "all-applications": {"fullname" : "All Applications", "shortname": "All Applications"}, "WB" : {"fullname" : "Western blot", "shortname":"WB"}, "ICCIF" : {"fullname" : "Immunocytochemistry/ Immunofluorescence", "shortname":"ICC/IF"} }, "product-promise": { "all": "all", "testedAndGuaranteed": "tested", "guaranteed": "expected", "predicted": "predicted", "notRecommended": "not-recommended" } }, "values": { "Mouse": { "WB-species-checked": "testedAndGuaranteed", "WB-species-dilution-info": "", "WB-species-notes": "

    ", "ICCIF-species-checked": "testedAndGuaranteed", "ICCIF-species-dilution-info": "", "ICCIF-species-notes": "

    " } } }

    产品用途HTML:

    产品实验方案

    For this product, it's our understanding that no specific protocols are required. You can visit:
    • Visit the General protocols
    • Visit the Troubleshooting

    产品详情HTML:

    产品详情

    What is this antibody validated in?
    Anti-iNOS antibody [NOS-IN] (ab49999) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Immunocytochemistry/immunofluorescence (ICC/IF) in Mouse samples.

    What is the molecular weight of iNOS?
    Anti-iNOS [NOS-IN] (ab49999) specifically detects a band for iNOS (UniProt: P35228) at a molecular weight of 131kDa.

    Trusted by the scientific community
    Anti-iNOS [NOS-IN] (ab49999) was first used in a scientific publication in 2007 and has been cited over 80 times in peer-reviewed journals.

    Reviewed by scientists
    Anti-iNOS [NOS-IN] (ab49999) has over 5 independent reviews from customers.

    性能和储存信息HTML:

    性能和储存信息

    形式
    Liquid
    纯化说明
    This antibody is purified from hybridoma cell culture.
    存储溶液
    pH: 7.4 Preservative: 0.087% Sodium azide Constituents: PBS
    运输条件
    Blue Ice
    推荐的短期储存时间
    1-2 weeks
    推荐的短期储存条件
    +4°C
    推荐的长期储存条件
    -20°C
    分装信息
    Upon delivery aliquot
    储存信息
    Avoid freeze / thaw cycle

    靶点信息HTML:

    靶点信息

    Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body (PubMed : 7503239). In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2 (PubMed : 16373578). As component of the iNOS-S100A8/9 transnitrosylase complex is involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM (By similarity). Involved in inflammation, enhances the synthesis of pro-inflammatory mediators such as IL6 and IL8 (By similarity).
    See full target information Nos2

    文献1:Materials today. Bio 35:102299 PubMed41019489 2025

    文献2:Ultrasound-activated piezoelectric scaffolds target dual Ca/NF-κB signaling pathways to orchestrate immunomodulation and osteogenesis for accelerated bone regeneration.

    文献3:Hui Zheng,Pengfei Yan,Peng Liu,Chang Yan,Mengqi Zhao,Zuyong Wang,Xiaofei Zheng,Huajun Wang,Rongkai Zhang,Luke P Lee,Swee Hin Teoh

    产品细节图片1

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    图标文献和实验
    该产品被引用文献
    官网有文献
    相关实验
    • Immunohistochemical Localization of NOS Isoforms

      Three distinct isoforms of nitric oxide synthases (NOS) have so far been identified and cloned (1 ). There are two constitutively expressed NOS—neuronal (n) and endothelial (e), NOS—and one inducible (i) form, iNOS

    • 人抗狂犬病毒抗体(anti-RV)酶联免疫分析(ELISA)

      人抗狂犬病毒抗体 (anti-RV) 酶联免疫分析( ELISA ) 试剂盒使用说明书 本试剂仅供研究使用         目的:本试剂盒用于测定人血清,血浆及相关液体样本中抗狂犬病毒抗体(anti-RV) 的含量。 实验原理:     本试剂盒应用双抗体夹心法测定标本中 人抗狂犬病毒抗体 (anti-RV) 水平。用纯化的 人狂犬病毒抗体 包被微孔板,制成固相抗体,往包被单抗的微孔中依次加入 犬狂犬病毒抗体

    • 人一氧化氮合成酶(T-NOS、iNOS、cNOS)酶联免疫分析(ELISA)

      人 一氧化氮合成酶(T -NOS 、iNOS 、cNOS) 酶联免疫分析( ELISA ) 试剂盒使用说明书 本试剂仅供研究使用         目的:本试剂盒用于测定人血清,血浆及相关液体样本中一氧化氮合成酶(T -NOS 、iNOS 、cNOS) 的 含量。 实验原理:   本试剂盒应用双抗体夹心法测定标本中人一氧化氮合成酶 (T - NOS 、 iNOS 、 cNOS) 水平。用纯化的人一氧化氮合成

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