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- 文献和实验
- 技术资料
- 库存:
42
- 供应商:
广州市左克生物
- 规格:
50 μl
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产品简介:
货号:A04902-50
产品名称:CELF 1 Antibody, mAb, Rabbit
产品规格:50 μl
产品介绍文本:RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative sp...
产品概述HTML:
| Specificity | This product is specific to CELF 1 |
| Host Species | Rabbit |
| Immunogen | A synthesized peptide derived from human CELF 1 |
| Species Reactivity | Human; Mouse; Rat |
| Conjugate | Unconjugated |
产品属性HTML:
| Form | Liquid |
| Storage Buffer | Supplied in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
| Storage Instructions | Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. |
| Purification | Affinity-chromatography |
| Isotype | Rabbit IgG |
| Clonality | Monoclonal |
产品简介HTML:
应用指导HTML:
技术背景HTML:
| Target Background | RNA-binding protein implicated in the regulation of several post-transcriptional events. Involved in pre-mRNA alternative splicing, mRNA translation and stability. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Acts both as an activator and as a repressor of a pair of coregulated exons: promotes inclusion of the smooth muscle (SM) exon but exclusion of the non-muscle (NM) exon in actinin pre-mRNAs. Activates SM exon 5 inclusion by antagonizing the repressive effect of PTB. |
| Synonyms | BRUNOL2; celf1; CUGBP; CUGBP1; EDEN BP; hNab50; NAB50; NAPOR; |
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