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- 技术资料
- 库存:
42
- 供应商:
广州市左克生物
- 规格:
100 μg
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产品简介:
货号:Z05647-100
产品名称:MICA alpha 3 mFc Chimera, Human
产品规格:100 μg
产品介绍文本:MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑li...
产品概述HTML:
产品属性HTML:
产品简介HTML:
| Species | Human | ||||
| Protein Construction |
|
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| Purity | > 95% as determined by BisTris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Biological Activity | Measured by its binding ability in a functional ELISA. Test result was comparable to standard batch. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 36.8 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
应用指导HTML:
技术背景HTML:
| Target Background | MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin. |
| Synonyms | MICA; MIC-A; MICA alpha 3 |
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文献和实验Introduction to Atomic Force Microscopy (AFM) in Biology
density of purple membrane to mica as a function of the electrolyte concentration. Two micrograms of protein was incubated for 5 min at room temperature on 6‐mm‐diameter supports in buffer containing different amounts of (A ) monovalent or (B ) divalent
, Salomon DS, Holland JF, Ohnuma T. Inhibitory effect of telomere-mimic phosphorothioate oligodeoxy nucleotides (S-ODNS) on human tumor cell lines. Oncology 1999;57(Suppl 2):27-36 6 Fearon KL, Hirschbein BL, Nelson JS, Foy MF, Nguyen MQ, Okruszek
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