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- GenScript/金斯瑞
- 中国
- Z05666-100
- 2026年08月19日
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- 技术资料
- 库存：
42
- 供应商：
广州市左克生物
- 规格：
100 μg
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产品简介:
货号：Z05666-100
产品名称：N Cadherin hFc Chimera, Human
产品规格：100 μg
产品介绍文本：Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and functional regulation of the nervous system, br...
产品概述HTML：
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产品简介HTML：
| Species | Human | ||||
| Protein Construction |
|
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| Purity | > 90% as determined by Bis-Tris PAGE | ||||
| Endotoxin Level | Less than 1EU per μg by the LAL method. | ||||
| Expression System | HEK293 | ||||
| Theoretical Molecular Weight | 88.56 kDa | ||||
| Apparent Molecular Weight | Due to glycosylation, the protein migrates to 100-120 kDa based on Bis-Tris PAGE result. | ||||
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). | ||||
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. | ||||
| Storage & Stability | Upon receiving, the product remains stable for 6 months at -20℃ or below. Upon reconstitution, the product should be stable for 3 months at -80℃. Avoid repeated freeze-thaw cycles. |
应用指导HTML：
技术背景HTML：
| Target Background | Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and functional regulation of the nervous system, brain, heart, skeletal muscles, blood vessels and hematopoietic microenvironment. |
| Synonyms | CDH2; N-cadherin; Neural cadherin; CD325; CDHN; CDw325; NCAD; |
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文献和实验with purified proteins. The methods described here overcome these problems. Using a mammalian expression system, a chimeric protein comprising the extracellular domain of E-cadherin fused at its C-terminus to the Fc domain of human IgG1 (E-cadherin∶Fc
grafts from the same patient (graft). Stains shown are hematoxylin and eosin (H&E) as well as antibody stains for ER, PR, HER2, cytokeratin (CK), E‐cadherin (E‐cad), β‐catenin (β‐cat), and human‐specific vimentin (hVim). Positive antibody signals
GPI蛋白 本文提供了有关糖基磷脂酰肌醇（GPI，是许多蛋白以及病毒蛋白结合于膜上的锚点）的信息。同时，网站还提供了许多相关链接和资源。 GPI overview GPI proteins in chickens GPI proteins in Drosophila GPI in prion proteins Human GPI proteins: protectin (CD59) and homologous restriction factor (HRF
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