- ¥560 - 11200
- Solarbio
- P04782
- 北京
- 2026年08月13日
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- 文献和实验
- 技术资料
- 库存：
999
- 英文名：
SATB1
- 保质期：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 供应商：
北京索莱宝科技有限公司
- 保存条件：
Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: <br>2-8°C for 2-7 days under sterile conditions after redissolves; <br>-20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; <br>-20°C to -70℃ for 12 months in lyophilized state.
- 规格：
10ug/50ug/100ug/1mg
| 规格： | 10ug | 产品价格： | ¥560.00 |
|---|---|---|---|
| 规格： | 50ug | 产品价格： | ¥1120.00 |
| 规格： | 100ug | 产品价格： | ¥1800.00 |
| 规格： | 1mg | 产品价格： | ¥11200.00 |
| 基因名 | SATB1 |
| 别名 | DNA-binding protein SATB1; Special AT-rich sequence-binding protein 1; |
| 蛋白号 | Q01826 |
| 种属 | Human |
| 宿主 | E.coli |
| 产品描述 | Recombinant Human SATB1 protein (Antigen) is produced by our E.coli expression system and the target gene encoding 1-313aa is expressed with a N-6His tag. |
| 区间范围 | 1-313aa |
| 标签信息 | N-6His |
| 预测分子量 | 34.32 kDa |
| 表观分子量 | 34 kDa |
| 纯度 | ≥85% by SDS-PAGE. |
| 内毒素 | Not measured |
| 溶剂 | Lyophilized from a 0.45μm filtered solution of 2-8M Urea, 20mM Tris-HCl, 150mM NaCl, PH7.2-8.0. |
| 复溶 | Reconstituted protein solution can be diluted with distilled water. Always centrifuge tubes before opening. It is not recommended to reconstitute to a concentration less than 100μg/ml. |
| 储存条件 | Upon receipt, store it immediately at -20°C or lower for long term storage. Please avoid repeated freeze-thaw cycles. This product is stable after storage at: 2-8°C for 2-7 days under sterile conditions after redissolves; -20°C for 1 months and -70℃ for 3 months under sterile conditions after redissolves; -20°C to -70℃ for 12 months in lyophilized state. |
| 运输条件 | 冷冻运输 |
| 背景说明 | Crucial silencing factor contributing to the initiation of X inactivation mediated by Xist RNA that occurs during embryogenesis and in lymphoma (By similarity). Binds to DNA at special AT-rich sequences, the consensus SATB1-binding sequence (CSBS), at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcriptional repressor controlling nuclear and viral gene expression in a phosphorylated and acetylated status-dependent manner, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes (e.g. PML at the MHC-I locus) and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers. Modulates genes that are essential in the maturation of the immune T-cell CD8SP from thymocytes. Required for the switching of fetal globin species, and beta- and gamma-globin genes regulation during erythroid differentiation. Plays a role in chromatin organization and nuclear architecture during apoptosis. Interacts with the unique region (UR) of cytomegalovirus (CMV). Alu-like motifs and SATB1-binding sites provide a unique chromatin context which seems preferentially targeted by the HIV-1 integration machinery. Moreover, HIV-1 Tat may overcome SATB1-mediated repression of IL2 and IL2RA (interleukin) in T-cells by binding to the same domain than HDAC1. Delineates specific epigenetic modifications at target gene loci, directly up-regulating metastasis-associated genes while down-regulating tumor-suppressor genes. Reprograms chromatin organization and the transcription profiles of breast tumors to promote growth and metastasis. Promotes neuronal differentiation of neural stem/progenitor cells in the adult subventricular zone, possibly by positively regulating the expression of NEUROD1 (By similarity). |
| 细胞活性 | Non-active. |
| ELISA活性 | No activity experimental data, to be verified. |
| SPR/BLI活性 | No activity experimental data, to be verified. |
| 研究领域 | 生物制药相关研究 |
| 英文名称 | SATB1 |
| 中文名称 | SATB1蛋白 |
| 单位 | 支 |
| 规格 | 10ug ; 50ug ; 100ug ; 1mg |
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