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- 文献和实验
- 技术资料
- 亚型:
IgG2, kappa
- 形态:
Liquid
- 保存条件:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term from the date of receipt..
- 克隆性:
Monoclonal
- 适应物种:
Human
- 保质期:
永久
- 目录编号:
HB791036
- 库存:
现货
- 供应商:
普健生物(武汉)科技有限公司
- 宿主:
Human
- 应用范围:
ELISA, FACS, Functional assay
- 靶点:
CD121 antigen-like family member A
- 抗体英文名:
Anti-Human CD121a/IL1R1 Reference Antibody (Tesrakitug, RUO)
- 抗体名:
抗人CD121a/IL1R1 参考抗体 (Tesrakitug, RUO)
- 规格:
100ug/1mg
| 规格: | 100ug | 产品价格: | ¥370.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥1484.0 |

| 产品名称 | Anti-Human CD121a/IL1R1 Reference Antibody (Tesrakitug, RUO) |
|---|---|
| 货号 | HB791036 |
| 宿主 | Human |
| 种属反应性 | Human |
| 免疫原 | \ |
| 形态 | Liquid |
| 纯度 | >95% as determined by SDS-PAGE. |
| 克隆性 | Monoclonal |
| 亚型 | IgG2, kappa |
| 应用 | ELISA, FACS, Functional assay |
| 靶点 | CD121 antigen-like family member A |
| 标记物 | \ |
abinScience, founded in 2023 in Strasbourg, France, is committed to developing and producing high-quality life science reagents. Rooted in one of Europe’s leading hubs for scientific innovation, abinScience empowers global research through reliable, efficient experimental solutions. Guided by the vision of “Empowering Bioscience Discovery,” we support scientists worldwide in advancing the frontiers of bioscience.
Technology and Innovation
Relying on the global leading position in antibody and protein research and more than 20 years of industry experience of its parent company ProteoGenix since 2003, abinScience has inherited advanced technologies and high-quality standards. In particular, the XtenCHO™ system developed by ProteoGenix, which has two modes of transient expression and stable expression, has been widely recognized as a core technology to improve the efficiency of protein production, providing a solid foundation for abinScience’s product line.
Product categories and application fields.
Main products.
10000+ high-activity proteins.
15000+ antibody series products:
Classic monoclonal antibody.
Monoclonal antibody
Internal control antibody, labeled antibody.
High-quality phosphorylation antibodies.
Highly specific nanobodies and small molecule antibodies.
Functional antibodies in vivo.
Low-background flow cytometry antibodies.
DNA/RNA antibodies and PEG antibodies.
1000+ reagent kit series products.
Large-scale packaging customization services: We offer personalized antibody design, protein production, molecular optimization, and experimental development services.
Application field
Infectious disease research: including viruses, superbugs, parasites, etc.
Neuroscience research: Supporting research on neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease.
Immunology research: Covers the research needs of immune activation, inhibition, and allergies and abnormal reactions.
Oncology research: Supporting the development of tumor biology and anti-tumor drugs.
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文献和实验因为抗体的结合而减少;在人体血清中无游离的CD20存在;最重要的是B淋巴细胞瘤上的CD20少有内吞和脱落的发生[ 2-5 ] 。1997年,以CD20为靶点的嵌合抗CD20单克隆抗体Rituxan已获准应用于B细胞淋巴瘤的治疗[ 6 ]。HI47(IgG3)是我所于1990年研制成功的国内第一个抗CD20鼠源性单克窿抗体,第四届国际人类白细胞分化抗原会议将HI47命名为CD20+X[ 7 ] 。我们利用噬菌体显示技术从HI47杂交瘤细胞中克隆到抗CD20抗体HI47可变区基因,将该基因构建成为嵌合的抗
20B淋巴细胞表面的膜蛋白CD20对B淋巴细胞的增殖和分化具有调节作用[1]。由于CD20分子仅在前-B淋巴细胞、未成熟B淋巴细胞、成熟B淋巴细胞、激活B淋巴细胞中表达,而在浆细胞、淋巴多能干细胞以及其它组织均无CD20的表达[2,3,4],在人体血清中亦无游离CD20的存在[5],因此CD20可作为B淋巴细胞瘤治疗的一个理想治疗靶点。限制抗体临床使用的因素主要有抗体产生的免疫原性和抗体的生产能力是否能够满足临床需要。第四届国际人类白细胞分化抗原会议将鼠源性单克隆抗CD20抗体HI47(IgG3)正式命名为CD20+X
CD11a/CD11b/CD11c 分子 CDlla 常用单克隆抗体或代号:MHM24, 2F12; CRIS―3(LFA―lα链,整合素α1) 主要表达细胞:Leu[A5] 分子质量(kDa)和结构:spl80(整合素α) 功 能:与1CAM-l(CD54)、ICAM-2(CDl02)、ICAM-3(C1350)结合,介导细胞黏附;与JAMl结合,参与白细胞穿过内皮细胞
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