Cathepsin D Antibody / CTSD 抗体,orb2642630,Biorbyt产品图

Cathepsin D Antibody / CTSD 抗体

,orb2642630,Biorbyt
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  • ¥8775
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  • orb2642630
  • 英国
  • 2026年08月07日
  • IHC-P
  • Mouse
  • Human
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 抗体名

      Cathepsin D Antibody / CTSD 抗体

    • 抗体英文名

      Cathepsin D Antibody / CTSD

    • 应用范围

      IHC-P

    • 宿主

      Mouse

    • 适应物种

      Human

    • 保质期

      12 months from date of receipt.

    • 抗原来源

      详询

    • 目录编号

      orb2642630

    • 级别

      科研

    • 库存

      99

    • 供应商

      Biorbyt

    • 标记物

      Unconjugated

    • 克隆性

      Monoclonal

    • 保存条件

      详询

    • 亚型

      Mouse IgG1, kappa

    • 免疫原

      详询

    • 规格

      7 ml

    类别: Antibodies

    产品子类型: Primary Antibody

    描述: Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins. It is synthesized as an inactive 43kDa preprocathepsin D that is cleaved and glycosylated to form a 46kDa procathepsin D and then further cleaved to produce 28kDa and 15kDa subunits (heavy and light chains, respectively). Cathepsin D exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease.

    克隆号: CTSD/2781

    应用稀释比例: The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    应用说明: Optimal dilution of the Cathepsin D antibody to be determined by the researcher.1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

    免疫原: A portion of amino acids 104-250 from the human protein was used as the immunogen for the Cathepsin D antibody.

    防腐剂: Prediluted in 1X PBS, 0.1 mg/ml rAlbumin, 0.05% sodium azide; For IHC use only

    纯化方法: Protein G affinity chromatography

    研究领域: Neuroscience

    UniProt ID: P07339

    保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

    备注: For research use only.

    产品细节图片1
    IHC testing of FFPE human renal cell carcinoma with Cathepsin D antibody (clone CTSD/2781). HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.

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    • 【求助】cathepsin 的相关转录因子有哪些?急!

      TFsearch TFfact 2、Sp1转录因子是参与真核细胞转录的高度相关锌指蛋白,以细胞和启动子特异性方式通过调控富含GC 启动子的基因表达,参与调节细胞功能如细胞增生、凋亡、分化和肿瘤形成. 有关sp1的综述介绍可下载:http://www.namipan.com/d/1641.pdf/0be61a85bb0cd70f115bf737c36a01f140e2f9f0a0410100 本文由丁香园论坛提供,想了解更多有用的、有意思的前沿资讯以及酷炫的实验

    • Antibody Conjugation

      8.0) in clean 16x125mm polypropylene test tube. If needed, adjust pH to 8.0 using 0.5M carbonate buffer. 2. Prepare fresh, 1mg/mL of either NHS-FITC in DMSO or 1mg/mL NHS-LC-Biotin in DH2O. If FITC coupling, add 75uL of FITC/DMSO solution to Antibody

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