- ￥8775
- Biorbyt
- orb2641311
- 英国
- 2026年08月07日
- IHC-P
- Mouse
- Human
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- 文献和实验
- 技术资料
- 抗体名：
StAR Antibody / Steroidogenic acute regulatory protein 抗体
- 抗体英文名：
StAR Antibody / Steroidogenic acute regulatory protein
- 应用范围：
IHC-P
- 宿主：
Mouse
- 适应物种：
Human
- 保质期：
12 months from date of receipt.
- 抗原来源：
详询
- 目录编号：
orb2641311
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
Monoclonal
- 保存条件：
详询
- 亚型：
Mouse IgG2b, kappa
- 免疫原：
详询
- 规格：
100 ug
产品子类型: Primary Antibody
描述: Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.
克隆号: STAR/2140
应用稀释比例: Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT
应用说明: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the StAR antibody to be titered up or down for optimal performance.
免疫原: A portion of amino acids 39-108 from the human protein was used as the immunogen for this StAR antibody.
防腐剂: 1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
纯化方法: Protein G affinity chromatography
研究领域: Cell Biology
UniProt ID: P49675
保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
备注: For research use only.
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文献和实验The steroidogenic acute regulatory (StAR) protein, a novel mitochondrial protein, is involved in the regulation of steroid hormone biosynthesis through its mediation of the intramitochondrial transport of the steroid substrate, cholesterol
Mapping Protein Distributions on Polytene Chromosomes by Immunostaining
for mapping distributions of chromosome-associated proteins, identifying and characterizing cis -regulatory DNA elements bound by particular proteins, and mapping functional protein domains necessary for chromosomal binding or other activities
Analysis of Trophoblast Giant Cell Steroidogenesis in Primary Cultures
acute regulatory protein (StAR) and 3β-hydroxysteroid dehydrogenase/isomerase (3βHSD). To obtain giant cells, uterine implantation sites are sliced in half, and the trophoblast giant cell layers are separated from the surrounding decidua by scraping
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