Recombinant Human CD30 Ligand/

产品简称：CD30 Ligand/TNFSF8

英文名称：Recombinant Human CD30 Ligand/TNFSF8 Protein(His Tag)

背景：CD30 ligand (CD30L), also known as CD153 and TNFSF8, is a membrane-associated glycoprotein belonging to the TNF superfamily and TNFR superfamily, and is a specific ligand for CD30/TNFRSF8 originally described as a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. CD30L is a type-II membrane glycoprotein expressed on activated T cells, stimulated monocyte-macrophages, granulocytes, eosinophils, and some Burkitt-like lymphoma cell lines. CD30L is capable of transducing signals throμgh CD30 on different CD30+ lymphoma cell lines, and mediates pleiotropic biologic effects including cell proliferation, activation, differentiation, as well as cell death by apoptosis. CD30-CD30 ligand interaction has been sμggested to have a pathophysiologic role in malignant lymphomas, particularly Hodgkin disease, large cell anaplastic lymphomas and Burkitt lymphomas, and is also involved in activation and functioning of the T cell-dependent immune response. Thus, CD153 and its receptor CD30 are regarded as therapeutic targets in hematologic malignancies, autoimmune and inflammatory diseases.

运输条件：This product is provided as lyophilized powder which is shipped with ice packs.

实验图：

Elabscience供应Recombinant Human CD30 Ligand/TNFSF8 Protein(His Tag)，这些蛋白质中的大多数纯度≥95%，内毒素水平≤1.0EU/μg，并且已经过活性验证，助力您科学实验。