重组含人高尔基关联PDZ 和卷曲螺旋基元蛋白(GOPC)

产品英文名称：
Recombinant Human Golgi-Associated PDZ and Coiled-Coil Motif Containing

英文简称:
GOPC

中文名称:
重组含人高尔基关联PDZ 和卷曲螺旋基元蛋白

背景资料:
GOPC is a PDZ domain-containing Golgi protein which binds the extreme C terminus of proteins in a sequence-specific manner. GOPC participates in intracellular protein tra大肠杆菌中重组表达icking and degradation. GOPC regulates CFTR chloride currents and acid-induced ACCN3 currents by modulating cell surface expression of both channels. GOPC regulates the intracellular tra大肠杆菌中重组表达icking of the ADR1B receptor. GOPC takes part in autophagy. GOPC over expression results in CFTR intracellular retention and degradation in the lysosomes.

产品描述:
GOPC Human Recombinant produced in E.Coli is a single， non-glycosylated polypeptide chain containing 198 amino acids （278-454 a.a.） and having a molecular mass of 21.5 kDa. The GOPC is fused to a 20 amino acid His Tag and purified by conventional chromatography.
来源宿主:
大肠杆菌中重组表达

溶解建议:
Sterile Filtered colorless solution. The GOPC protein solution contains 20mM Tris-HCl pH-8， 1mM DTT and 10% glycerol.

保存建议：
GOPC although stable 4℃ for 4 weeks， should be stored desiccated below -18℃. For long term storage it is recommended to add a carrier protein （0.1% HSA or BSA）. Please prevent freeze-thaw cycles.
应用领域：
重组含人高尔基关联PDZ 和卷曲螺旋基元蛋白产品可广泛应用于信号传导研究、药物靶点研究、功能研究、蛋白互作研究、ELISA检测、Western Blot、免疫组化等生物医学研究领域。

关键词：
重组含人高尔基关联PDZ 和卷曲螺旋基元蛋白、Recombinant Human Golgi-Associated PDZ and Coiled-Coil Motif Containing、GOPC、重组蛋白、多肽、受体蛋白、原核表达、His标签

其他简介：

 
CMBIO