重组人维生素D受体(VDR)

产品英文名称：
Recombinant Human Vitamin D Receptor

英文简称:
VDR

中文名称:
重组人维生素D受体

背景资料:
Vitamin D receptors （VDRs） belong to the NR1I family， which also includes pregnane X （PXR） and constitutive androstane （CAR） receptors which form heterodimers with members of the retinoid X receptor family. VDR is expressed in the intestine， thyroid and kidney and has an imperative role in calcium homeostasis. VDRs inhibit expression of 1alpha-hydroxylase （the proximal activator of 1，25（OH）2D3 and induce expression of the 1，25（OH）2D3 inactivating enzyme CYP24. Additionally， VDR has recently bVitamin D Receptor Human Recombinant produced in E.Coli is a full length protein consisting of 427 amino acids having a molecular weight of 48.3kDa and fused with 5.5kDa amino-terminal His-Flag tag. VDR is purified by proprietary chromatographic techniques.n recognized as an additional bile acid receptor alongside FXR and may function to protect gut against the toxic and carcinogenic e大肠杆菌中重组表达ects of these endobiotics. Hereditary mutations in the VDR gene leads to rickets， which is typified by muscle weakness， growth retardation， bone deformity and secondary hyperparathyroidism. The human gene encoding the VDR is localized to chromosome 12q12-q14.

产品描述:
Vitamin D Receptor Human Recombinant produced in E.Coli is a full length protein consisting of 427 amino acids having a molecular weight of 48.3kDa and fused with 5.5kDa amino-terminal His-Flag tag. VDR is purified by proprietary chromatographic techniques.
来源宿主:
大肠杆菌中重组表达

溶解建议:
提供的重组人维生素D受体产品形式为经无菌过滤处理的无色溶液.

保存建议：
重组人维生素D受体产品在4℃保存请2 - 4周内将使用；-20℃可长期保存.产品若长期保存，建议添加载体蛋白（0.1% HSA或BSA）.避免反复冻融.
应用领域：
重组人维生素D受体产品可广泛应用于信号传导研究、药物靶点研究、功能研究、蛋白互作研究、ELISA检测、Western Blot、免疫组化等生物医学研究领域。

关键词：
重组人维生素D受体、Recombinant Human Vitamin D Receptor、VDR、重组蛋白、受体蛋白、原核表达、标签蛋白、CMBIO

其他简介：

 
CMBIO