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- 文献和实验
- 技术资料
- 保存条件:
2-8度
- 保质期:
1年
- 英文名:
Myoglobin
- 库存:
999
- 供应商:
上海淳麦生物
- 规格:
/5ug/20ug/1mg
Human Myoglobin
英文简称:
Myoglobin
中文名称:
人肌红蛋白
背景资料:
Myoglobin is a member of the globin superfamily and can be found in skeletal and cardiac muscles. It is a haemoprotein that contributs to intracellular oxygen storage and transcellular facilitated di人心脏组织中提取纯化usion of oxygen. Myoglobin has a single-chain globular structure of 153 amino acids, containing a heme prosthetic group (iron-containing porphyrin) in the core around which the remaining apoprotein folds. Myoglobin has 8 alpha helices and a hydrophobic core. Myoglobin’s molecular weight is 16.7 kDa, and it is the primary oxygen-carrying pigment of muscle tissues. The binding of oxygen in myoglobin is di人心脏组织中提取纯化erent from the cooperative oxygen binding in hemoglobin, since positive collaboration is a property of multimeric/oligomeric proteins only. Instead, the binding of oxygen by myoglobin is uninfluenced by the oxygen pressure in the surrounding tissue. Myoglobin is frequently referred to as having an "instant binding tenacity" to oxygen given its hyperbolic oxygen dissociation curve. Di人心脏组织中提取纯化erent organisms are able to hold their breaths longer due to high concentrations of myoglobin in their muscle cells. Myoglobin is responsible for the pigments that make meat red. The color of the meat is partly determined by the charge of the iron atom in myoglobin and the oxygen attached to it. Myoglobin is found in Type I muscle, Type II A and Type II B, but it is mostly dHuman Myoglobin produced in Human Cardiac Tissues having a molecular mass of 17.5kDa. Myoglobin is released from recently injured myocardial cells within a few hours of Infarction. Peak levels are reached more quickly than CK-MB or Troponin complex.med that myoglobin is not found in smooth muscle. Myoglobin is discharged from damaged muscle tissue (rhabdomyolysis), which contains very high concentrations of myoglobin. Even though the released myoglobin is filtered by the kidneys, it is toxic to the renal tubular epithelium and thus may cause acute renal failure.
产品描述:
Human Myoglobin produced in Human Cardiac Tissues having a molecular mass of 17.5kDa. Myoglobin is released from recently injured myocardial cells within a few hours of Infarction. Peak levels are reached more quickly than CK-MB or Troponin complex.
来源宿主:
人心脏组织中提取纯化
溶解建议:
Sterile Filtered red solution. The protein solution is in 0.05M phosphate buffer containing 0.15M NaCl and 0.09% NaN3 pH 7.5. Filtered through a 0.2uM membrane.
保存建议:
Human Myoglobin should be stored at 2-8℃.
应用领域:
人肌红蛋白产品可广泛应用于免疫检测研究、抗体开发、ELISA检测、Western Blot、免疫组化等生物医学研究领域。
关键词:
人肌红蛋白、Human Myoglobin、Myoglobin、蛋白质/抗原/多肽、CMBIO、淳麦生物、科研试剂、生物试剂
其他简介:
CMBIO




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文献和实验与血红蛋白相似的血红素蛋白质。存在于肌肉细胞内,可作为结晶体分离出来。分子量1万 7千,每 1分子含 1个血红素,与血红素作为四聚体活动不同,肌红蛋白是单体。人的肌红蛋白每 1分子含 1分子半胱氨酸,而马和抹香鲸的肌红蛋白则完全不含半胱氨酸。 J. C. Kendrew等( 1958— 1963)通过 X线衍射,已弄清抹香鲸肌红蛋白结晶的立体结构。蛋白质部分的珠蛋白是由 153个氨基酸残基组成的一条多肽链,铁血红素一方面和此链中的一个组氨酸,另一方面通过 H2 O和另一个组氨酸形成配位
上海西唐生物科技有限公司 021-55229872, 65333639 www.westang.com 猪肌红蛋白 ( Myoglobin )ELISA 试剂盒 ( 用于血清、血浆、细胞培养上清液和其它生物体液内 ) 原理 本实验采用双抗体夹心 ABC-ELISA 法。用抗猪 Myoglobin 单抗包被于酶标板上,标准品和样品中的 Myoglobin与单抗结合
Myoglobin represents the stores of oxygen in muscle tissues. Because of its relatively small mol wt, myoglobin is often used in electrophoretic techniques as a mol wt marker, and also as a test for separation efficiency in capillary
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