- ￥10764
- Biorbyt
- orb1249512
- 英国
- 2026年07月31日
- ELISA, IHC, WB
- Goat
- Human
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- 文献和实验
- 技术资料
- 抗体名：
FAS Antibody 抗体
- 抗体英文名：
FAS Antibody
- 靶点：
FAS
- 浓度：
500 ug/mL
- 应用范围：
ELISA, IHC, WB
- 宿主：
Goat
- 适应物种：
Human
- 保质期：
12 months from date of receipt.
- 抗原来源：
详询
- 目录编号：
orb1249512
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
Polyclonal
- 保存条件：
详询
- 形态：
Liquid
- 免疫原：
详询
- 规格：
0.1 mg
产品子类型: Primary Antibody
描述: FAS Antibody
别名: FAS, Fas (TNF receptor superfamily, member 6), ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6, APO-1 cell surface antigen, CD95 antigen, Fas AMA, Fas antigen, OTTHUMP00000020045, OTTHUMP00000020046, OTTHUMP00000020051, OTTHUMP00000059646, apoptosis antigen 1, tumor necrosis factor receptor superfamily member 6, tumor necrosis factor receptor superfamily, member 6
应用说明: Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Approx 37kDa band observed in lysates of cell line MOLT4 (calculated MW of 37.7kDa according to NP_000034.1). Recommended concentration: 0.1-0.3µg/mL. Primary incubation was 1 hour.Immunohistochemistry:Paraffin embedded Human Tonsil and Small Intestine. Recommended concentration: 3.75µg/mL.
免疫原: The immunogen for this antibody is: KTCRKHRKENQGSH
防腐剂: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH 7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
纯化方法: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
特异性: This antibody is expected to recognize reported isoforms 1 (NP_000034.1), 2 (NP_690610.1) and 3 (NP_690611.1).
研究领域: Cell Biology
UniProt ID: P25445
NCBI 参考序列: NP_000034.1, NP_690611.1, NP_690610.1
保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
备注: For research use only.
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文献和实验an important role in regulation of the immune system. In the method described, hepatoma MH134 (Fas− and FasL− ) is transfected with murine Fas and FasL cDNA. A single administration of monoclonal anti-Fas antibody efficiently suppresses the growth of F6b (MH134
and inhibit concomitant progressive tissue destruction. Of particular interest in this respect is the use of the so-called single-chain fragments of variable region (scFv) antibody fragments for the targeted reactivation of Fas-dependent activation-induced
cell membrane-associated molecules that transduce apoptotic signals, e.g., Fas Ligand (FasL) or TRAIL (reviewed in refs. 1 ,2 ). Target cell recognition by NK cells occurs via either of two ways: (1) receptors capable of binding molecules
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