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- Biorbyt
- orb1152528
- 英国
- 2026年07月27日
- ELISA, FC, IHC
- Human
- Human
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- 技术资料
- 抗体名：
Anti-erbB-2 (Her-2/neu) [4D5-8 (trastuzumab)] 抗体
- 抗体英文名：
Anti-erbB-2 (Her-2/neu) [4D5-8 (trastuzumab)]
- 靶点：
erbB-2 (Her-2/neu)
- 浓度：
1 mg/ml
- 应用范围：
ELISA, FC, IHC
- 宿主：
Human
- 适应物种：
Human
- 保质期：
12 months from date of receipt.
- 抗原来源：
详询
- 目录编号：
orb1152528
- 级别：
科研
- 库存：
99
- 供应商：
Biorbyt
- 标记物：
Unconjugated
- 克隆性：
Monoclonal
- 保存条件：
详询
- 亚型：
Human IgG2a
- 免疫原：
详询
- 规格：
0.2 mg
类别: Antibodies
描述: Mouse monoclonal antibody to erbB-2
克隆号: 4D5-8 (trastuzumab)
别名: CD340; Metastatic lymph node gene 19 protein (MLN 19); Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; p185HER2; EGFR
免疫原: A431 cells (human epidermoid carcinoma) (over)expressing EGFR.
防腐剂: PBS with 0.02% Proclin 300.
纯度: Purified
特异性: Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30% of invasive breast cancers and 70% of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder.
研究领域: Signal Transduction
UniProt ID: P04626
保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
备注: For research use only.
描述: Mouse monoclonal antibody to erbB-2
克隆号: 4D5-8 (trastuzumab)
别名: CD340; Metastatic lymph node gene 19 protein (MLN 19); Proto-oncogene Neu; Proto-oncogene c-ErbB-2; Tyrosine kinase-type cell surface receptor HER2; p185erbB2; p185HER2; EGFR
免疫原: A431 cells (human epidermoid carcinoma) (over)expressing EGFR.
防腐剂: PBS with 0.02% Proclin 300.
纯度: Purified
特异性: Oncogenic protein Her-2/neu (erbB-2), a member of the family of epidermal growth factor (EGF) receptors, overexpressed in 30% of invasive breast cancers and 70% of ductal carcinomata in situ, in a small percentage of melanomas, and in other malignancies originating from various organs, including ovary, kidney, colon, and bladder.
研究领域: Signal Transduction
UniProt ID: P04626
保存条件: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
备注: For research use only.
Immunohistochemical staining of paraffin embedded human breast tissue using anti-erbB-2 antibody 4D5-8 (trastuzumab) Anti-erbB-2 (Her-2/neu) staining of paraffin embedded human breast tissue using the rabbit-chimeric version of 4D5-8 (trastuzumab) (orb348902). Antigen retreival was achieved by microwaving in citrate buffer (pH6), followed by blocking with protein block serum-free buffer. Primary antibody incubation with orb348902 was carried out at 4 µg/ml for 30 minutes. Samples were then incubated with an anti-rabbit IgG HRP secondary antibody for 20 mins followed by DAB (3, 3′-diaminobenzidine), and counter-staining with haemotoxylin. Weak membrane staining exclusively of ductal epithelial cells may be observed. Recommended concentration, 4-6 µg/ml.
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Anti-erbB-2 (Her-2/neu) [4D5-8 (trastuzumab)] 抗体，orb1152528，Biorbyt
￥7254
