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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
2-8°C
- 英文名:
Cholesterol Concentrate, Porcine (LDL)
- 规格:
100 mg, 1 g, 5 g, 10 g
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文献和实验的调节作用:①通过抑制HMG�CoA还原酶(HMG�Coa reductase)活性,减少细胞内胆固醇的合成;②激活脂酰CoA胆固醇酯酰转移酶(acyl CoA:cholesterol acyltransferase,ACAT)使胆固醇生成胆固醇酯而贮存;③抑制LDL受体蛋白基因的转录,减少LDL受体蛋白的合成,降低细胞对LDL的摄取(图5-6)。 除上述有受体介导的LDL代谢途径外,体内内皮网状系统的吞噬细胞也可摄取LDL(多为经过化学修饰的LDL),此途径生成的胆固醇不具有上述调节
Characterization of Whole Body Cholesterol Fluxes in the Mouse
is characterized by excessive cholesterol accumulation in the vessel wall. Current therapies mainly aim at decreasing influx through lowering plasma LDL?cholesterol levels. The challenge is to develop therapeutic interventions to increase efflux of excess
Using Surface Electrodes to Monitor the Electric-Pulse-Induced Permeabilization of Porcine Skin
(1 ,2 ). Densely packed layers of flattened, dead, keratinized cells (2 ,3 ) are incorporated into a lipid lamellae matrix consisting primarily of ceramides, cholesterol, and fatty acids (2 ,4 ), forming an impermeable, hydrophobic partition. The stratum
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