- ￥800
- DIMA BIOTECH/缔码生物
- 武汉
- BME100100
- 2026年07月10日
- ELISA; Flow Cyt
- Humanized
- Human
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- 文献和实验
- 技术资料
- 免疫原：
inquire
- 亚型：
Human IgG2 - Kappa
- 形态：
Powder
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 级别：
Research use only
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 宿主：
Humanized
- 应用范围：
ELISA; Flow Cyt
- 浓度：
详见COA
- 靶点：
CEACAM6
- 抗体英文名：
Anti-CEACAM6(tinurilimab biosimilar) mAb
- 抗体名：
Anti-CEACAM6(tinurilimab biosimilar) mAb
- 规格：
50μg
| 产品类型 | Biosimilar reference antibodies |
|---|---|
| 靶点 | CEACAM6 |
| Uniprot ID | P40199 |
| 背景 | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| 通用名 | BAY-1834942 |
| 货期 | In Stock |
| 产品英文名称 | Anti-CEACAM6(tinurilimab biosimilar) mAb |
| 内毒素 | Less than 1.0 EU/μg by the LAL method. For <1 EU/mg requirements, please contact us for customization. |
| 保质期 | 12 months from date of dispatch |
| 无菌性 | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| 储存与运输 | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| 别名 | CD66c;CEAL;NCA |
| 应用 | ELISA; Flow Cyt |
| 有无偶联 | Unconjugated |
| 组分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 宿主种属 | Humanized |
| IgG亚型 | Human IgG2 - Kappa |
| 反应种属 | Human |
| 推荐稀释比 | ELISA 1:5000-10000; Flow Cyt 1:100 |
| 应用范围 | Research use only |
Figure 1. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CEACAM6 Protein, His Tag PME100822 can bind Anti-CEACAM6 Neutralizing antibody ( BME100100) in a linear range of 0.61–156.25 ng/mL.
Figure 2. Flow cytometry analysis with 1 μg/mL Anti-CEACAM6 (tinurilimab biosimilar) mAb (BME100100) on HEK293 cells transfected with Human CEACAM6 protein (Blue histogram) or HEK293 transfected with irrelevant protein (Red histogram).
Figure 3. Flow cytometry analysis of antigen binding of anti-human CEACAM6 mAb(BME100100). (A) BME100100 does not bind to Jurkat cells that do not express CEACAM6. (B) A clear peak shift of BME100100 was seen compared to the control when incubated with CEACAM6-expressing TT cells, indicating strong binding of BME100100 to CEACAM6. Antibodies were incubated at 5 μg/mL.
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文献和实验不止是粒细胞标志物！CEACAM8在脓毒症诊断与肿瘤免疫中的最-新研究进展
1.1 CEACAM8的结构 癌胚抗原相关细胞粘附分子8（CEACAM 8）是免疫球蛋白超家族的CEA家族中的一个成员，属于GPI锚定的高度糖基化蛋白质，又被称为CD66b、NCA-95或CD67。CEACAM 8具有11个N-糖基化位点，其分子量为95kDa。一些研究提出了一种纯化CEACAM8的方法，可用于进一步研究其结构和功能，并在蛋白质水平证实了CEACAM8是CGM6（NCA-W272）基因的产物。此外，研究表明，CEACAM8可能调节CEACAM6的顺式和反式相互作用，并可能
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