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- DIMA BIOTECH/缔码生物
- 武汉
- BME100030
- 2026年07月10日
- Flow Cyt
- Humanized
- Human
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AJE 润色服务限时 8 折起，权威机构信任 15+ 年Cytoscape 教程来了！快速实现顶刊同款通路网络图五大应用案例：Mustang Q 膜层析应用全解析1 个小工具，一次性搞定流程图、质粒图谱和信号通路图- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
inquire
- 亚型：
Human IgG1 - kappa
- 形态：
Powder
- 保存条件：
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- 克隆性：
Monoclonal
- 标记物：
Unconjugated
- 适应物种：
Human
- 级别：
Research use only
- 库存：
In Stock
- 供应商：
缔码生物（武汉）科技有限公司
- 宿主：
Humanized
- 应用范围：
Flow Cyt
- 浓度：
详见COA
- 靶点：
CD52
- 抗体英文名：
Anti-CD52 (alemtuzumab biosimilar) mAb
- 抗体名：
Anti-CD52 (alemtuzumab biosimilar) mAb
- 规格：
50μg
| 产品类型 | Biosimilar reference antibodies |
|---|---|
| 靶点 | CD52 |
| Uniprot ID | P31358 |
| 背景 | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| 通用名 | Campath-1H, LDP-03 |
| 货期 | In Stock |
| 产品英文名称 | Anti-CD52 (alemtuzumab biosimilar) mAb |
| 内毒素 | Less than 1.0 EU/μg by the LAL method. For <1 EU/mg requirements, please contact us for customization. |
| 保质期 | 12 months from date of dispatch |
| 无菌性 | Products are supplied non-sterile. For cell culture applications, dilute in appropriate medium and sterile-filter (0.22 µm) prior to use. |
| 储存与运输 | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| 别名 | CDW52;HE5;CD52;CAMPATH-1 antigen |
| 应用 | Flow Cyt |
| 有无偶联 | Unconjugated |
| 组分 | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| 宿主种属 | Humanized |
| IgG亚型 | Human IgG1 - kappa |
| 反应种属 | Human |
| 推荐稀释比 | Flow Cyt 1:100 |
| 应用范围 | Research use only |
Figure 1. HEK293 cell line transfected with irrelevant protein (B) and human CD52 (A) were surface stained with Anti-CD52 mAb 1 μg/ml (alemtuzumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验CD52 分子 常用单克隆抗体或代号： YTH66.9;(Campath- 1) 主要表达细胞： Leu,Eo [NL] 分子质量(kDa)和结构： gp25- 29 功 能： 补体介导溶解作用的靶分子 Aka Campath-1 CD52 antibodies are lytic for target cells, both with human complement and via antibody dependent cellular
Alemtuzumab (Campath), the humanized rat monoclonal antibody that targets the CD52 surface antigen, is currently used for treatment of patients with resistant chronic lymphocytic leukemia. Monitoring levels of the antibody in plasma/serum
单克隆抗体单克隆抗体药物一直都是免疫治疗的热点，也成为医药巨头竞争的前沿阵地。 1997 年：FDA 批准的针对 CD20 的利妥昔单抗。 80 年代后期：针对 HER2，CD52，EGFR 和 VEGFR 的单抗每个都是重磅炸弹。 2013 年：从肿瘤药销售额前20名来看（如下图），前三名重磅炸弹均来自于单克隆抗体药物。而针对肿瘤免疫疗法 BMS 的Yervoy 自 2011 年上市以来成为后起之秀，也标志着癌症免疫疗法的开端。 癌症免疫疗法被各大
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