Recombinant Mouse Siglec-10 Protein产品图

Recombinant Mouse Siglec-10 Pr

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  • ¥950 - 3000
  • ABclonal
  • RP03262
  • 2026年07月13日
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      10 μg/50 μg

    规格:10 μg产品价格:¥950.0
    规格:50 μg产品价格:¥3000.0
    Siglecs (sialic acid binding Ig-like lectins) belong to the immunoglobulin superfamily. Siglec-G is the apparent ortholog of human Siglec-10. It is expressed by mature B cells, but significant levels of transcript were also detected in DC, myeloid cells, and to a lesser extent, T cells. Mature Siglec-G consists of a 526 amino acid (aa) extracellular domain (ECD), a 21 aa transmembrane segment, and a 124 aa cytoplasmic domain. Siglec-G is a member of the CD33-related Siglec family in the mouse, and is involved in negative regulation of B-cell antigen receptor signaling and specifically acts on B1 cells to inhibit Ca2+ signaling, cellular expansion and antibody secretion.

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