- ￥546 - 4464
- TargetMol
- T73809
- 2026年07月07日
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- CAS号：
108320-87-2
- 规格：
1mg/5mg/10mg/25mg
| 规格： | 1mg | 产品价格： | ￥546.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥1880.0 |
| 规格： | 10mg | 产品价格： | ￥2792.0 |
| 规格： | 25mg | 产品价格： | ￥4464.0 |
Product Introduction
Bioactivity
| 名称 | UDP-GalNAc disodium |
| 描述 | UDP-GalNAc disodium is a key sugar nucleotide and serves as the catalytic substrate of EpsC115 (a truncated mutant protein of extracellular polymeric substance (EPS) with amino acids 1–115 at the N-terminus). It is a universal glycosyl donor for various N-acetylgalactosaminyltransferases, mediating the transfer of GalNAc groups from nucleotide sugars to carbohydrate or polypeptide receptors and providing essential glycosyl precursors for various glycosylation modification reactions. At present, UDP-GalNAc disodium has been widely applied in mechanism research of colorectal cancer, breast cancer and other tumors. |
| 体外活性 | 方法：以终浓度 25 μM 的 UDP-GalNAc disodium为底物，利用纯化的 ppGalNAc-T2、ppGalNAc-T3 蛋白开展体外糖基化反应实验 。 结果：25 μM UDP-GalNAc disodium可作为反应底物，应用于 ppGalNAc-T2 与 ppGalNAc-T3 的体外糖基化功能验证 [3]。 |
| 存储条件 | Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | H2O : 100 mg/mL (153.53 mM), Sonication is recommended. |
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文献和实验Transcriptional Regulation of UDP-Glucuronosyltransferases
the expression of UGT1A loci. This chapter presents an overview of the most recent developments in our understanding of transcriptional regulation of UDP-glucuronosyltransferase (UGT) genes, and specifically focuses on the regulation of UGTs via NRs
The Use of Hepatocytes to Investigate UDP-Glucuronosyltransferases and Sulfotransferases
. This system theoretically expresses the full complement of drug-metabolizing enzymes associated with the endoplasmic reticulum (CYP and UDP-glucuronosyltransferases) or located in the cytosolic compartment (sulfotransferases), and relevant accessory proteins required
Glucuronidation of Fatty Acids and Prostaglandins by Human UDP-Glucuronosyltransferases
glucuronidation from both human liver micro-somes and human recombinant UDP-glucuronosyltransferase 2B7 (UGT2B7) are presented. Several unique methods for synthesis of FAs that are not commercially available are also described. Moreover, comprehensive methods
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