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文献和实验Cell-Based Assays for Regulators of Tau Biology
, which may ultimately lead to translational outcomes for AD. In particular, the intracellular microtubule-associated protein tau that accumulates in AD is found in normal cells. Manipulating these cells may allow us to address basic questions about tau biology
strategies. EGFR mutation profiling assesses gefitinib or erlotinib efficacy in non-small cell lung cancer patients. Tumor genotyping of multiple genes and/or mutations, however, is not widely deployed due to the high cost of analyzing these regions
Introduction of human 14-3-3 proteins
The human and bovine 14-3-3 eta protein mRNAs are highly conservedEvolutionary conservation of the 14-3-3 proteinExpression and structural analysis of 14-3-3 proteinsCrystal structure of the zeta isoform of the 14-3-3 proteinStructure of a 14
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