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- T13554
- 2026年07月07日
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- CAS号：
289893-26-1
- 规格：
1mg/1mLx10mM(inDMSO)/5mg/10mg/25mg/50mg/100mg
| 规格： | 1mg | 产品价格： | ￥252.0 |
|---|---|---|---|
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥530.0 |
| 规格： | 5mg | 产品价格： | ￥472.0 |
| 规格： | 10mg | 产品价格： | ￥713.0 |
| 规格： | 25mg | 产品价格： | ￥1480.0 |
| 规格： | 50mg | 产品价格： | ￥2304.0 |
| 规格： | 100mg | 产品价格： | ￥3480.0 |
Product Introduction
Bioactivity
| 名称 | Arimoclomol maleate |
| 描述 | Arimoclomol maleate (BRX-220) (BRX-220) is a heat shock protein (HSP) co-inducer. |
| 体内活性 | Arimoclomol, administered for 5 d, has a protective effect against CCK-induced acute pancreatitis. Repeated CCK treatment results in the typical laboratory and morphological changes of experimentally induced pancreatitis. The pancreatic levels of HSP60 and HSP72 are significantly increased in the animals treated with Arimoclomol [1]. Arimoclomol is a co-inducer of heat shock proteins for the potential treatment of amyotrophic lateral sclerosis (ALS), the most common form of motor neuron disease [2]. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 5 mg/mL (11.63 mM), Sonication is recommended. DMSO : 145 mg/mL (337.33 mM), Sonication is recommended. 10% DMSO+90% Saline : 10 mg/mL (23.26 mM), Solution. |
| 关键字 | ubiquitin | system | protein | proteasome | neurons | motor | misfolded | Inhibitor | inhibit | HSP | Heat shock proteins | co-inducer | clearance | BRX220 | BRX 220 | assemblies | Arimoclomol maleate | Arimoclomol | aggregation |
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| 相关库 | Anti-Cancer Approved Drug Library | Bioactive Compound Library | Bioactive Compounds Library Max | Failed Clinical Trials Compound Library | NO PAINS Compound Library | FDA-Approved Drug Library | Immunology/Inflammation Compound Library | Membrane Protein-targeted Compound Library | Orally Active Compound Library | Drug Repurposing Compound Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Drug Library |
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化合物 Arimoclomol maleate【289893-26-1】
￥252 - 3480
