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- 2026年07月07日
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- 文献和实验
- 技术资料
- CAS号：
6753-98-6
- 规格：
1mLx10mM(inDMSO)/5mg/10mg/25mg/50mg/100mg/200mg
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥172.0 |
|---|---|---|---|
| 规格： | 5mg | 产品价格： | ￥132.0 |
| 规格： | 10mg | 产品价格： | ￥170.0 |
| 规格： | 25mg | 产品价格： | ￥252.0 |
| 规格： | 50mg | 产品价格： | ￥334.0 |
| 规格： | 100mg | 产品价格： | ￥604.0 |
| 规格： | 200mg | 产品价格： | ￥872.0 |
Product Introduction
Bioactivity
| 名称 | α-Humulene |
| 描述 | α-Humulene (Alpha-caryophyllene) is extracted from S.officinalis essential oil.α-Humulene can inhibit tumor cell growth.α-Humulene also shows anti-inflammatory effects, probably by interfering with TNFalpha production and COX-2 and iNOS expression. |
| 体外活性 | S. officinalis精油通过水蒸气蒸馏法得到，并通过柱色谱法进行分馏。通过气相色谱(GC)联用质谱(MS)对精油及其各分馏部分进行了分析。在MCF-7乳腺癌细胞株、HCT-116结肠癌细胞株以及RAW264.7小鼠巨噬细胞株上，采用MTT法评估了其细胞毒性活性。结果表明：含有α-萜品烯的S. officinalis精油子分馏部分F1.1.1对RAW264.7和HCT-116展现出最高活性，IC(50)值分别为41.9和77.3 mu g/ml。而含有反式-石竹烯(Alpha-caryophyllene)的S. officinalis精油子分馏部分F1.2.1在RAW246.7和HCT-116上的活性较低，IC(50)值分别为90.5和145.8 mu g/ml。 |
| 存储条件 | Store at low temperature,Keep away from moisture,Keep away from direct sunlight Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | Ether : Soluble DMSO : 50 mg/mL (244.68 mM), Sonication is recommended. Ethanol : Soluble 10% DMSO+90% Corn Oil : 2.5 mg/mL (12.23 mM), Sonication is recommended. |
| 关键字 | α-Humulene | αHumulene | α-Caryophyllene | α Humulene | TNF-α | NOS | NO Synthase | Nitric oxide synthases | iNOS | Inhibitor | inhibit | Humulene | Cyclooxygenase | COX | alpha-Humulene | a-Humulene | a-caryophyllene |
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| 相关库 | Neuroprotective Compound Library | Bioactive Compound Library | Anti-Cancer Active Compound Library | Food as Medicine Compound Library | Anti-Tumor Natural Product Library | Anti-Aging Compound Library | Flavor Natural Product library | Natural Product Library | Immunology/Inflammation Compound Library | Terpene Natural Product Library | Pain-Related Compound Library | Natural Product Library for HTS |
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文献和实验引物二聚体带，并且降低引物有效浓度而使PCR 反应不能正常进行[8]。 （8）对引物的修饰一般是在5’端增加酶切位点，应根据下一步实验中要插入PCR 产物的载体的相应序列。 1.1.1 PCR 的引物设计 首先从GenBank 查到VI 型 胶原蛋白 的α1 链的mRMA 序列，序列号为 NM_001848 .其序列长为 4164bp，其中98 到3184 为VI 型胶原蛋白的α1链
Replication timing by density transfer
), arrest with 200 nM alpha factor (1-1.25 doubling times, until % unbudded cells stops increasing). NOTE: This alpha factor concentration is for bar1 strains. BAR1+ strains require 15x more alpha factor. 3. Filter, wash in Ycomp+alpha factor, resuspend
1578.89 1641.88 1758.98 1994.08 2558.37 2581.36 2594.50 2597.50 2722.33 检索参数 Database searched SWISSPROTTaxonomy Mus musculusEnzyme trypsinMax missed cleavages 1 or 2Fixed modifications are CarbamidomethylProtein mass NonePeptide mass tolerance ±
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