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- 文献和实验
- 技术资料
- CAS号:
50-07-7
- 规格:
1mg/1mLx10mM(inDMSO)/5mg/10mg/25mg/50mg
| 规格: | 1mg | 产品价格: | ¥164.0 |
|---|---|---|---|
| 规格: | 1mLx10mM(inDMSO) | 产品价格: | ¥984.0 |
| 规格: | 5mg | 产品价格: | ¥327.0 |
| 规格: | 10mg | 产品价格: | ¥517.0 |
| 规格: | 25mg | 产品价格: | ¥880.0 |
| 规格: | 50mg | 产品价格: | ¥1328.0 |
Product Introduction
Bioactivity
| 名称 | Mitomycin C |
| 描述 | Mitomycin C (Ametycine) is an antineoplastic agent and DNA double-strand crosslinking agent capable of inducing DNA damage, inhibiting DNA synthesis, suppressing mitosis, and activating apoptosis. It is commonly employed as a chemotherapeutic drug. Mitomycin C is a broad-spectrum antibiotic effective against both Gram-negative and Gram-positive bacteria. |
| 存储条件 | Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 41.66 mg/mL (124.59 mM), Sonication and heating are recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 2 mg/mL (5.98 mM), Sonication is recommended. |
| 关键字 | MitomycinC | DNAAlkylator | DNA/RNA Synthesis | DNA synthesis | DNA Alkylator/Crosslinker | DNA Alkylator | Crosslinker | Bacterial | Apoptosis | Antibiotic | ADC Cytotoxin |
| 相关产品 | Guanidine hydrochloride | Aceglutamide | Levulinic acid | Neomycin sulfate | Terbinafine hydrochloride | Dimethyl sulfoxide | Sodium bicarbonate | Hyaluronic acid sodium (MW 20 kDa) | Thymidine | Sodium diacetate | Sulfamethoxazole sodium | D(+)-Raffinose pentahydrate |
| 相关库 | Microbial Natural Product Library | Anti-Cancer Approved Drug Library | Bioactive Compound Library | Anti-Cancer Active Compound Library | Bioactive Compounds Library Max | Anti-Bacterial Compound Library | FDA-Approved & Pharmacopeia Drug Library | FDA-Approved Drug Library | Antioxidant Compound Library | Drug Repurposing Compound Library | Natural Product Library for HTS | Anti-Cancer Drug Library |
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文献和实验3.73 3.61 3.51 3.44 3.37 3.28 3.18 3.07 2.96 2.85 2.72 12 13 4.96 4.35 4.00 3.77 3.60 3.48 3.39 3.31 3.25 3.15 3.05 2.95 2.84 2.72 2.59 13 14 4.86 4.24 3.89 3.66 3.50 3.38 3.28 3.21 3.15 3.05 2.95 2.84 2.73 2.61 2.49 14 15 4.76 4.15 3.80
- - - - - - 10nM 10nM 10nM hEGF - - - - - - 50ng/ml 50ng/ml 50ng/ml C029 hHGF - - - - - 10ng/ml 25ng/ml 25ng/ml 25ng/ml CJ72 B-27 - - - 1% 1% - 1× 1× 1× A83-01
胸膜间皮瘤为胸膜原发性肿瘤,是来源于脏层、壁层、纵隔或横膈四部分胸膜的肿瘤。国外发病率高于国内,各为0.07~0.11%和0.04%。死亡率占全世界所有肿瘤的1%以下。近年有明显上升趋势。50岁以上多见,男女之比为2:1。与石棉接触有关。目前,恶性型尚缺乏有效的治疗方法。 临床表现 1.局限型者可无明显不适或仅有胸痛、活动后气促。 2.弥漫型者有较剧烈胸痛、气促、消瘦等。 3.患侧胸廓活动受限,饱满,叩诊浊音,呼吸音减低或消失。 4.可有锁骨上窝及腋下淋巴结肿大。 诊断
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