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- CAS号:
943820-93-7
- 规格:
1mLx10mM(inDMSO)/1mg/5mg/10mg/25mg/50mg/100mg/500mg
| 规格: | 1mLx10mM(inDMSO) | 产品价格: | ¥912.0 |
|---|---|---|---|
| 规格: | 1mg | 产品价格: | ¥412.0 |
| 规格: | 5mg | 产品价格: | ¥936.0 |
| 规格: | 10mg | 产品价格: | ¥1592.0 |
| 规格: | 25mg | 产品价格: | ¥2624.0 |
| 规格: | 50mg | 产品价格: | ¥3688.0 |
| 规格: | 100mg | 产品价格: | ¥4736.0 |
| 规格: | 500mg | 产品价格: | ¥9440.0 |
Product Introduction
Bioactivity
| 名称 | Wnt/β-catenin agonist 2 |
| 描述 | Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and is an effective Wnt agonist. Wnt/β-catenin agonist 2 can be used in the study of diseases related to signal transduction and is closely related to cancer invasion and metastasis. |
| 体外活性 | Wnt/β-catenin agonist 2 acts as a stimulator of β-Catenin in the SW480 cell line, enhancing its activity. Moreover, it has been observed that Wnt/β-catenin agonist 2 exerts an influence on the differentiation of ST2 cells, promoting their transformation into osteoblasts [1]. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | 10% DMSO+90% Saline : < 10 mg/mL (36.73 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. DMSO : 150 mg/mL (550.94 mM), Sonication is recommended. 10% DMSO+40% PEG300+5% Tween 80+45% Saline : 10 mg/mL (36.73 mM), Solution. |
| 关键字 | βcatenin | Wnt/β-catenin agonist 2 | Wnt/βcatenin agonist 2 | Wnt/β-catenin | Wnt/β catenin agonist 2 | Wnt/beta-catenin agonist 2 | Wnt/betacatenin | Wnt/b-catenin agonist 2 | Wnt/b-catenin | Wnt | GSK-3 | GSK3 | beta-catenin | betacatenin | bcatenin |
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文献和实验miaoduan 本人刚刚开始做实验,有关wnt通路的检测,想请教激活wnt通路的方法,看资料主要有三种: 1,加wnt蛋白 2,LiCl抑制gsk3β 3,转染wnt质粒或者点突变的β-catenin质粒 不知哪种方法可行,具体如何操作呢 非常感谢!!! edwardellen 加wnt3a,看过一篇CANCER CELL是这样激活的 liubodoctor
a look from the following website just by clicking "Tyrosine Phosphorylation and Dimerization" http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WSN-43F85YV-2&_user=1111158&_coverDate=06%2F29%2F2001&_rdoc=1&_fmt=full&_orig=search
3K-AKT以及Rho GTPase等非经典通路产生效应。 核心节点:TGF-β受体、SMAD2/3、SMAD4 主要功能:细胞分化、组织修复、免疫调控、细胞外基质重塑和纤维化 疾病关联:TGF-β在肿瘤早期可能具有抑制作用,而在部分晚期肿瘤中又可能促进侵袭、转移和免疫逃逸。 和元小贴士:TGF-β最值得注意的地方不是信号链条有多长,而是同一信号在不同生物学环境下可能产生完全不同的结果。 04 Wnt/β-catenin信号通路
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