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- 2026年07月07日
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- 文献和实验
- 技术资料
- CAS号：
627085-15-8
- 规格：
1mLx10mM(inDMSO)/1mg/5mg/10mg/25mg/50mg/100mg/200mg
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥1608.0 |
|---|---|---|---|
| 规格： | 1mg | 产品价格： | ￥624.0 |
| 规格： | 5mg | 产品价格： | ￥1384.0 |
| 规格： | 10mg | 产品价格： | ￥2056.0 |
| 规格： | 25mg | 产品价格： | ￥3288.0 |
| 规格： | 50mg | 产品价格： | ￥4680.0 |
| 规格： | 100mg | 产品价格： | ￥6496.0 |
| 规格： | 200mg | 产品价格： | ￥8720.0 |
Product Introduction
Bioactivity
| 名称 | OT-551 HCl |
| 描述 | OT-551 HCl is an NF-Κb inhibitor, a disubstituted hydroxylamine with antioxidant properties can be used for the treatment of cataracts and age-related macular degeneration and geographic atrophy (GA). |
| 体内活性 | OT-551 HCl (intraperitoneally injected; rats; approximately 30 min prior to a 6 h exposure to 2700 lux white fluorescent light) significantly reduced the number of RPE cell nuclei in light-exposed eyes from water-treated animals. RPE damage index was significantly lower in the animals treated with any dose of OT-551 HCl compared to water-treated animals both in the inferior and superior hemispheres. Systemic administration of OT-551 HCl provides RPE cell protection against acute light damage.[1] |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 3.6 mg/mL (12.96 mM), Sonication is recommended. |
| 关键字 | OT-551 HCl | NF-κB | NFκB | NF-kB | NFkB | 627085-11-4 Free base | 627085-11-4 |
| 相关产品 | D-Psicose | Uridine | Sodium propionate | Ethyl palmitate | 1,4-Naphthoquinone | Glucosamine | Undecane | Fumaric acid | Kojic acid | Magnesium sulfate | Ethyl linoleate | N,N-Dimethylacetamide |
| 相关库 | Inhibitor Library | Bioactive Compound Library | Bioactive Compounds Library Max | Transcription Factor-Targeted Compound Library | ReFRAME Related Library | Anti-Aging Compound Library | HIF-1 Signaling Pathway Compound Library | Clinical Compound Library | Immunology/Inflammation Compound Library | Drug Repurposing Compound Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Drug Library |
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的 Na2HPO4·12H2O,充分混合即为0.2mol/L的PB（pH约为7.4～7.5）。若pH偏高或偏低，可通过改变二者的比例来加以调整，室温 保存即可。 2．0.01mol/L磷酸盐缓冲生理盐水（Phosphate Buffered Saline, PBS） 试剂：0.2mol/L PB 50ml NaCl 8.5～9g(约0.15mol/L) 重蒸水 至1000ml 配制方法：称取NaCl 8.5～9g及0.2mol/L的PB 50ml，加入
3dCsv0oa0K/SASPFgw5eAjyccPfMLqyavxf7R49BqQoH0J3/fyZ517iDxBPgb4fEs+OWkQn4OmDv9lfQKlcXOe2vw+rIO3QcY0qnzIorgZ9OYfXeX8j9+z6+1puOKQ1yh34QK24KSR6patWqUh9Xr15Ncl+p1YGvry8JBUpQJ6FBPLS1Q6OSJlST4+NDX6zPnuPly5d488YJri6uePv2Le7euYN1q0Ojj6mQFiVXrlwoWKggSpQsiRo1aqBR48
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OT-551盐酸盐【627085-15-8】
￥624 - 8720
