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- TargetMol
- T1068
- 2026年07月07日
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- 文献和实验
- 技术资料
- CAS号：
1143-38-0
- 规格：
1mLx10mM(inDMSO)/50mg/100mg/500mg
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥197.0 |
|---|---|---|---|
| 规格： | 50mg | 产品价格： | ￥163.0 |
| 规格： | 100mg | 产品价格： | ￥282.0 |
| 规格： | 500mg | 产品价格： | ￥572.0 |
Product Introduction
Bioactivity
| 名称 | Dithranol |
| 描述 | Dithranol (cignoline) is an anthracene derivative that disrupts MITOCHONDRIA function and structure and is used for the treatment of DERMATOSES, especially PSORIASIS. It may cause FOLLICULITIS. |
| 激酶实验 | THP-1 and HEK293 cells are transiently transfected using DEAE-dextran and Polyfect reagent, respectively. Plasmids transfected contain genes coding for the NF-κB-dependent pELAM-luc luciferase reporter, TLR2, TLR4, CD14, and MD2. Cells (5×105 THP-1 or 1×105 HEK293) are added to 12-well plates, washed after 18 h, and stimulated for 5 h. Cells are then lysed with reporter lysis buffer as directed, and lysates are analyzed for luminescence using Promega luciferase substrate and a Monolight 3010 luminometer. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | Chloroform : 41 mg/mL (181.23 mM), Sonication is recommended. DMSO : 10 mM, Sonication is recommended. 10% DMSO+90% Corn Oil : 1 mg/mL (4.42 mM), Sonication is recommended. |
| 关键字 | RNASynthesis | RNA Synthesis | replication | repair | psoriatic | plaques | Inhibitor | inhibit | DNASynthesis | DNA/RNA Synthesis | DNA Synthesis | DNA | Dithranol |
| 相关产品 | Carbazole | Hexane-1,6-diol | Guanidine hydrochloride | Vidarabine | 1,4-Naphthoquinone | 5-Fluorouracil | Usnic Acid | Adenine hemisulfate | Erythromycin thiocyanate | Adenine | Docosanoic acid | Thymidine |
| 相关库 | Microbial Natural Product Library | Bioactive Compound Library | Anti-Cancer Approved Drug Library | Bioactive Compounds Library Max | EMA Approved Drug Library | Anti-Tumor Natural Product Library | Anti-Aging Compound Library | Natural Product Library | Immunology/Inflammation Compound Library | Drug Repurposing Compound Library | Natural Product Library for HTS | Polyphenolic Natural Product Library |
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Prediction of Protein‐Protein Interaction Networks
methods for predicting protein‐protein interactions. Bioinformatics 21:i38‐i46. Berger, J.M., Gamblin, S.J., Harrison, S.C., and Wang, J.C. 1996. Structure and mechanism of DNA
Capture and Qualitative Analysis of the Activated Fc Receptor Complex from Live Cells
Ash, K., Berger, T., Munn, R.J., and Horner, C.M. 1994. Isolation and partial purification of plasma membrane from porcine oocytes. Mol. Reprod. Dev. 38:334‐337.
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