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- T0983L
- 2026年07月07日
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- CAS号：
52-66-4
- 规格：
5mg/10mg/25mg/50mg/100mg/500mg
| 规格： | 5mg | 产品价格： | ￥106.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥164.0 |
| 规格： | 25mg | 产品价格： | ￥332.0 |
| 规格： | 50mg | 产品价格： | ￥476.0 |
| 规格： | 100mg | 产品价格： | ￥714.0 |
| 规格： | 500mg | 产品价格： | ￥1432.0 |
Product Introduction
Bioactivity
| 名称 | DL-Penicillamine |
| 描述 | DL-Penicillamine (3-Sulfanylvaline) is a chelating agent recommended for the removal of excess copper in patients with Wilson's disease. DL-Penicillamine is only found in individuals that have used or taken this drug. It is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease. From in vitro studies which indicate that one atom of copper combines with two molecules of DL-penicillamine. DL-Penicillamine also reduces excess cystine excretion in cystinuria. This is done, at least in part, by disulfide interchange between DL-penicillamine and cystine, resulting in the formation of penicillamine-cysteine disulfide, a substance that is much more soluble than cysteine and is excreted readily. DL-Penicillamine interferes with the formation of cross-links between tropocollagen molecules and cleaves them when newly formed. The mechanism of action of DL-penicillamine in rheumatoid arthritis is unknown although it appears to suppress disease activity. Unlike cytotoxic immunosuppressants, DL-penicillamine markedly lowers IgM rheumatoid factor but produces no significant depression in absolute levels of serum immunoglobulins. Also unlike cytotoxic immunosuppressants which act on both, DL-penicillamine in vitro depresses T-cell activity but not B-cell activity. |
| 存储条件 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | H2O : 5 mM, Sonication is recommended. DMSO : Insoluble |
| 关键字 | DL-Penicillamine | DLPenicillamine | DL Penicillamine | antibiotic |
| 相关产品 | Penicillin G sodium salt | Penicillin G potassium | Ampicillin | Doxycycline | Neomycin sulfate | Terbinafine hydrochloride | Metronidazole | Ethyl acetoacetate | EDTA copper(II) disodium salt | Ampicillin sodium | Sulfamethoxazole sodium | Kanamycin sulfate |
| 相关库 | Bioactive Compound Library | Bioactive Compounds Library Max | ReFRAME Related Library | Anti-Infection Compound Library | Approved Drug Library | NO PAINS Compound Library | FDA-Approved Drug Library | Antidepressant Compound Library | Drug Repurposing Compound Library | Anti-Metabolism Disease Compound Library | Cuproptosis Compound Library | NMPA-Approved Drug Library |
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文献和实验.1 14.9 14.7 14.6 14.5 14.5 14.4 14.3 14.2 14.2 14.1 14.0 13.9 3 4 10.6 9.98 9.60 9.36 9.20 9.07 8.98 8.90 8.84 8.75 8.66 8.56 8.46 8.36 8.26 4 5 8.43 7.76 7.39 7.16 6.98 6.85 6.76 6.68 6.62 6.52 6.43 6.33 6.23 6.12 6.01 5 6 7.26 6.60 5.23
The OP9-DL1 System: Generation of T-Lymphocytes from Embryonic or Hematopoietic Stem Cells In Vitro
The OP9-DL1 System: Generation of T-Lymphocytes from Embryonic or Hematopoietic Stem Cells In VitroRoxanne HolmesandJuan Carlos Zúñiga-Pflücker1 Sunnybrook Research Institute and Department of Immunology, University of Toronto, Toronto, Ontario M4
0.0351 5.66 (1)2.20(COOH) (2)9.11(NH 2 ) (3)10.07(OH) L- 酪氨酸 L-tyrosine(Try) 181.19 342.4d 0.045 5.66 DL- 缬氨酸 DL-valine(Val) 117.15 293d 7.04 5.96 (1)2.32(2)9.62 L- 缬氨酸 L-
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