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- CAS号：
54767-75-8
- 规格：
1mLx10mM(inDMSO)/10mg
| 规格： | 1mLx10mM(inDMSO) | 产品价格： | ￥168.0 |
|---|---|---|---|
| 规格： | 10mg | 产品价格： | ￥135.0 |
Product Introduction
Bioactivity
| 名称 | Suloctidil |
| 描述 | Suloctidil is a peripheral vasodilator that was formerly used in the management of peripheral and cerebral vascular disorders. It is hepatotoxic and fatalities have occurred. |
| 激酶实验 | Protein Kinase profiling assay: Assay for 22 different proteins kinases is carried out by ProQinase Gmbh. All of the protein kinases are expressed either in Sf9 insect cells or in E.coli as recombinant GST-fusion proteins or His-tagged proteins. Protein kinases are purified by affinity chromatography using either GSH-agarose or Ni_NTH-agarose. A radiometric protein kinase assay is used for measuring the kinase activity of the 22 protein kinases. Briefly, for each protein kinase, 50 μL reaction cocktail containing 60 mM HEPES-NaOH, 3 mM MgCl2, 3 mM MnCl2, 3 μM Na-orthovanadate, 1.2 mM DTT, 50 μg/mL PEG20000, 1 μM [γ-33P]-ATP, Niclosamide, adequate amount of enzyme and its substrate. The PKC-alpha assay additionally contain 1 mM Cacl2, 4 mM EDTA, 5 μg/mL phosphatidylserine and 1 μg/mL 1, 2-Dioleyl-glycerol. The reaction cocktails are incubated at 37 °C for 60 minutes and stop with 50 μL 2% (v/v) H3PO4. Incorporation of 33Pi is determined with a microplate scintillation counter. The activities and the IC50 values are calculated using Quattro Workflow V2.28. |
| 存储条件 | Store at low temperature Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| 溶解度 | DMSO : 50 mg/mL (148.12 mM), Sonication is recommended. |
| 关键字 | Suloctidil | Sodium potassium pump | Plateletaggregation | Platelet aggregation | Na+/K+ ATPase | Inhibitor | inhibit |
| 相关产品 | Chlorpropamide | Sodium orthovanadate | 2,3-Butanedione 2-Monoxime | Oleic acid | Revaprazan hydrochloride | Quinine | Tolbutamide | Cyclocreatine | Permethrin | trans-Aconitic acid | Sodium oleate | Phlorizin |
| 相关库 | Drug-induced Liver Injury (DILI) Compound Library | ReFRAME Related Library | Coagulation and Anticoagulation Compound Library | Anti-COVID-19 Compound Library | NO PAINS Compound Library | Withdrawn Drug Library | Multi-Target Compound Library |
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舒洛地尔【54767-75-8】
￥135 - 168
